دورية أكاديمية
Ultrasound-guided foam sclerotherapy for the treatment of chronic venous ulceration: a preliminary study.
| العنوان: | Ultrasound-guided foam sclerotherapy for the treatment of chronic venous ulceration: a preliminary study. |
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| المؤلفون: | Darvall KA; Birmingham University, Department of Vascular Surgery, Heart of England NHS Trust, Birmingham, UK. katydarvall@btinternet.com, Bate GR, Adam DJ, Silverman SH, Bradbury AW |
| المصدر: | European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery [Eur J Vasc Endovasc Surg] 2009 Dec; Vol. 38 (6), pp. 764-9. Date of Electronic Publication: 2009 Jul 18. |
| نوع المنشور: | Clinical Trial; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: England NLM ID: 9512728 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2165 (Electronic) Linking ISSN: 10785884 NLM ISO Abbreviation: Eur J Vasc Endovasc Surg Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2002-: London : Elsevier Original Publication: London, UK : W.B. Saunders Co. Ltd., c1995- |
| مواضيع طبية MeSH: | Sclerotherapy* , Ultrasonography, Interventional*, Varicose Ulcer/*therapy, Adult ; Aged ; Aged, 80 and over ; Chronic Disease ; Combined Modality Therapy ; Female ; Humans ; Male ; Middle Aged ; Pilot Projects ; Prospective Studies ; Recurrence ; Severity of Illness Index ; Stockings, Compression ; Time Factors ; Treatment Outcome ; Ultrasonography, Doppler, Duplex ; Varicose Ulcer/diagnostic imaging ; Varicose Ulcer/physiopathology ; Wound Healing ; Young Adult |
| مستخلص: | Objectives: When compared to compression therapy alone, surgical correction of superficial venous reflux (SVR) reduces recurrence but does not appear to increase healing of chronic venous ulceration (CVU). The role of ultrasound-guided foam sclerotherapy (UGFS) of SVR as part of the treatment of CVU remains uncertain. The aim of this study is to describe CVU healing and recurrence rates after UGFS and to relate these outcomes to patterns of pre- and post-intervention venous reflux. Methods: A prospective study of 27 consecutive patients (28 legs) of median age 69 (interquartile range 54-79) years undergoing UGFS for SVR in addition to compression for treatment of CVU of median duration 12 (IQR 6-23) months. Prior to and 1, 6, and 12 months after treatment patients underwent clinical and duplex assessment. Results: 8 limbs (29%) had deep and superficial venous reflux, and 20 limbs had SVR alone. There was a history of DVT in 4 limbs, and 4 patients were on warfarin. No limbs had significant arterial disease and all received post-UGFS compression. Median volume of (3% STD) foam used was 8 (range 2-14) ml. 1, 3 and 6 months after UGFS, 22 (79%), 27 (96%) and 27 (96%) CVU had healed. At 12 months, 25 ulcers remained healed, 2 ulcers had recurred; one patient had died from carcinomatosis. Discussion: Following UGFS as an adjunct to compression, 96% of CVU healed within 3 months and only 2 healed ulcers (7%) had recurred at 12 months. UGFS appears to be an attractive minimally-invasive alternative to surgery to treat SVR in patients with CVU, especially the elderly and frail. |
| تواريخ الأحداث: | Date Created: 20090721 Date Completed: 20091217 Latest Revision: 20220318 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.ejvs.2009.05.027 |
| PMID: | 19616975 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1532-2165 |
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| DOI: | 10.1016/j.ejvs.2009.05.027 |