دورية أكاديمية
The use of serology as an additional tool to support diagnosis of difficult multibacillary leprosy cases: lessons from clinical care.
| العنوان: | The use of serology as an additional tool to support diagnosis of difficult multibacillary leprosy cases: lessons from clinical care. |
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| المؤلفون: | Oliveira ML; Dermatology Department, Medical School, Federal University of Rio de Janeiro, RJ, Rio de Janeiro, Brazil. mleide@hucff.ufrj.br, Cavaliére FA, Maceira JM, Bührer-Sékula S |
| المصدر: | Revista da Sociedade Brasileira de Medicina Tropical [Rev Soc Bras Med Trop] 2008; Vol. 41 Suppl 2, pp. 27-33. |
| نوع المنشور: | Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Sociedade Brasileira de Medicina Tropical Country of Publication: Brazil NLM ID: 7507456 Publication Model: Print Cited Medium: Internet ISSN: 1678-9849 (Electronic) Linking ISSN: 00378682 NLM ISO Abbreviation: Rev Soc Bras Med Trop Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <1997-> : Uberaba, MG, Brazil : Sociedade Brasileira de Medicina Tropical Original Publication: Rio De Janeiro : Sociedade Brasileira De Medicina Tropical |
| مواضيع طبية MeSH: | Antigens, Bacterial*/immunology , Glycolipids*/immunology, Antibodies, Bacterial/*blood , Leprosy, Borderline/*diagnosis , Leprosy, Lepromatous/*diagnosis , Mycobacterium leprae/*immunology, Adult ; Aged ; Child ; Diagnosis, Differential ; Female ; Humans ; Immunoglobulin M/blood ; Leprosy, Borderline/microbiology ; Leprosy, Borderline/pathology ; Leprosy, Lepromatous/microbiology ; Leprosy, Lepromatous/pathology ; Male ; Middle Aged ; Sensitivity and Specificity ; Skin/microbiology ; Skin/pathology |
| مستخلص: | Seven multibacillary leprosy and two suspected cases assisted in different situations during clinical care activities at the university in Rio de Janeiro city are described. All cases presented some difficulties for diagnosis, since they evolved with few or no cardinal signs or symptoms of leprosy. A serological test used as an auxiliary tool was helpful in the diagnosis or exclusion procedure of each case, facilitating academic discussions at the time of case examination. Considering serology and bacilloscopy (skin smear) as the only rapid and relatively cheap available tests for confirmation of atypical MB leprosy, the advantages and disadvantages of their use were discussed. Both tests support the diagnostic procedure and the classification of cases for treatment purposes. The advantage of bacilloscopy is its capacity for diagnosis confirmation. The advantages of serology are: (a) its applicability for direct use by health workers, providing immediate results; (b) the potential for patient participation in the process; and (c) it provides a learning opportunity, allowing for improved teaching of leprosy pathogenesis. |
| المشرفين على المادة: | 0 (Antibodies, Bacterial) 0 (Antigens, Bacterial) 0 (Glycolipids) 0 (Immunoglobulin M) 0 (phenolic glycolipid I, Mycobacterium leprae) |
| تواريخ الأحداث: | Date Created: 20090721 Date Completed: 20091015 Latest Revision: 20190907 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1590/s0037-86822008000700007 |
| PMID: | 19618072 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1678-9849 |
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| DOI: | 10.1590/s0037-86822008000700007 |