دورية أكاديمية
Enhanced imaging in low dose electron microscopy using electron counting.
| العنوان: | Enhanced imaging in low dose electron microscopy using electron counting. |
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| المؤلفون: | McMullan G; MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK. gm2@mrc-lmb.cam.ac.uk, Clark AT, Turchetta R, Faruqi AR |
| المصدر: | Ultramicroscopy [Ultramicroscopy] 2009 Nov; Vol. 109 (12), pp. 1411-6. Date of Electronic Publication: 2009 Jul 15. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7513702 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-2723 (Electronic) Linking ISSN: 03043991 NLM ISO Abbreviation: Ultramicroscopy Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Amsterdam : Elsevier Original Publication: Amsterdam, North-Holland. |
| مواضيع طبية MeSH: | Electrons*, Microscopy, Electron/*methods, Computer Simulation |
| مستخلص: | We compare the direct electron imaging performance at 120keV of a monolithic active pixel sensor (MAPS) operated in a conventional integrating mode with the performance obtained when operated in a single event counting mode. For the combination of sensor and incident electron energy used here, we propose a heuristic approach with which to process the single event images in which each event is renormalised to have an integrated weight of unity. Using this approach we find enhancements in the Nyquist frequency modulation transfer function (MTF) and detective quantum efficiency (DQE) over the corresponding integrating mode values by factors of 8 and 3, respectively. |
| References: | Ultramicroscopy. 2007 Aug;107(8):674-84. (PMID: 17346890) Ultramicroscopy. 2007 Apr-May;107(4-5):401-13. (PMID: 17140733) Methods Cell Biol. 2007;79:661-719. (PMID: 17327180) J Struct Biol. 2008 Mar;161(3):352-8. (PMID: 18054249) Ultramicroscopy. 2009 Aug;109(9):1126-43. (PMID: 19497671) |
| معلومات مُعتمدة: | MC_U105184321 United Kingdom MRC_ Medical Research Council; MC_U105184322 United Kingdom MRC_ Medical Research Council |
| تواريخ الأحداث: | Date Created: 20090804 Date Completed: 20100217 Latest Revision: 20211028 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC2868354 |
| DOI: | 10.1016/j.ultramic.2009.07.004 |
| PMID: | 19647366 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1879-2723 |
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| DOI: | 10.1016/j.ultramic.2009.07.004 |