دورية أكاديمية
The role of modifiable pre-pregnancy risk factors in preventing adverse fetal outcomes among women with type 1 and type 2 diabetes.
| العنوان: | The role of modifiable pre-pregnancy risk factors in preventing adverse fetal outcomes among women with type 1 and type 2 diabetes. |
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| المؤلفون: | Inkster ME; Division of Community Health Sciences, University of Dundee, MacKenzie Building, Kirsty Semple Way, Dundee, DD2 4BF, UK., Fahey TP, Donnan PT, Leese GP, Mires GJ, Murphy DJ |
| المصدر: | Acta obstetricia et gynecologica Scandinavica [Acta Obstet Gynecol Scand] 2009; Vol. 88 (10), pp. 1153-7. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley Country of Publication: United States NLM ID: 0370343 Publication Model: Print Cited Medium: Internet ISSN: 1600-0412 (Electronic) Linking ISSN: 00016349 NLM ISO Abbreviation: Acta Obstet Gynecol Scand Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2011- : Malden, MA : Wiley Original Publication: Copenhagen : Munksgaard |
| مواضيع طبية MeSH: | Pregnancy Outcome/*epidemiology, Abortion, Spontaneous/prevention & control ; Adolescent ; Adult ; Body Mass Index ; Congenital Abnormalities/epidemiology ; Diabetes Mellitus, Type 1 ; Diabetes Mellitus, Type 2 ; Female ; Glycated Hemoglobin ; Humans ; Pregnancy ; Pregnancy in Diabetics ; Risk Factors ; Smoking/epidemiology ; Stillbirth/epidemiology ; Young Adult |
| مستخلص: | We investigated the fetal outcomes of pregnancy in women with pre-existing diabetes in relation to pre-pregnancy risk factors using a community-based cohort of women in Tayside, Scotland. There were 211 pregnancies in 132 women with insulin-requiring type 1 and 2 diabetes between January 1993 and December 2005. Adverse fetal outcome was classified as spontaneous miscarriage, termination for medical reasons, stillbirth, neonatal death, or congenital malformation and occurred in 61 (29%) pregnancies. Mothers with poor glycemic control pre-conceptually and at booking (HbA(1c)=7.5%) had almost a three-fold increase in adverse fetal outcome compared with mothers having fair control, odds ratio (OR) 2.59 (95% CI 1.11-6.03), and 2.71 (95% CI 1.39-5.28), respectively. Mothers who were still smoking at the booking visit had a two-fold increase in adverse fetal outcome (OR 2.12, 95% CI 1.09-4.10). Further improvement in the management of diabetes and pregnancy is needed through enhanced preconception services addressing the full spectrum of modifiable risk factors. |
| المشرفين على المادة: | 0 (Glycated Hemoglobin A) |
| تواريخ الأحداث: | Date Created: 20090807 Date Completed: 20091209 Latest Revision: 20221207 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1080/00016340903176859 |
| PMID: | 19657757 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher | تدمد: | 1600-0412 |
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| DOI: | 10.1080/00016340903176859 |