دورية أكاديمية
أعرض في EDS

Aqueous extract of brazilian green propolis: primary components, evaluation of inflammation and wound healing by using subcutaneous implanted sponges.

التفاصيل البيبلوغرافية
العنوان: Aqueous extract of brazilian green propolis: primary components, evaluation of inflammation and wound healing by using subcutaneous implanted sponges.
المؤلفون: de Moura SA; Department of General Pathology, Institute of Biological Sciences, Federal University of Minas Gerais-UFMG, Belo Horizonte, Brazil., Negri G, Salatino A, Lima LD, Dourado LP, Mendes JB, Andrade SP, Ferreira MA, Cara DC
المصدر: Evidence-based complementary and alternative medicine : eCAM [Evid Based Complement Alternat Med] 2011; Vol. 2011, pp. 748283. Date of Electronic Publication: 2011 Jun 08.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Hindawi Pub Country of Publication: United States NLM ID: 101215021 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1741-4288 (Electronic) Linking ISSN: 1741427X NLM ISO Abbreviation: Evid Based Complement Alternat Med Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: 2011- : New York, NY : Hindawi Pub.
Original Publication: Oxford, UK : Oxford University Press, c2004-
مستخلص: Propolis is a chemically complex resinous bee product which has gained worldwide popularity as a means to improve health condition and prevent diseases. The main constituents of an aqueous extract of a sample of green propolis from Southeast Brazil were shown by high performance liquid chromatography/mass spectroscopy/mass spectroscopy to be mono- and di-O-caffeoylquinic acids; phenylpropanoids known as important constituents of alcohol extracts of green propolis, such as artepillin C and drupanin were also detected in low amounts in the aqueous extract. The anti-inflammatory activity of this extract was evaluated by determination of wound healing parameters. Female Swiss mice were implanted subcutaneously with polyesther-polyurethane sponge discs to induce wound healing responses, and administered orally with green propolis (500 mg kg(-1)). At 4, 7 and 14 days post-implantation, the fibrovascular stroma and deposition of extracellular matrix were evaluated by histopathologic and morphometric analyses. In the propolis-treated group at Days 4 and 7 the inflammatory process in the sponge was reduced in comparison with control. A progressive increase in cell influx and collagen deposition was observed in control and propolis-treated groups during the whole period. However, these effects were attenuated in the propolis-treated group at Days 4 and 7, indicating that key factors of the wound healing process are modulated by propolis constituents.
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تواريخ الأحداث: Date Created: 20090820 Date Completed: 20120823 Latest Revision: 20231105
رمز التحديث: 20231105
مُعرف محوري في PubMed: PMC3137525
DOI: 10.1093/ecam/nep112
PMID: 19690045
قاعدة البيانات: MEDLINE
الوصف
تدمد:1741-4288
DOI:10.1093/ecam/nep112