دورية أكاديمية
Uterine artery embolization versus laparoscopic occlusion of uterine arteries for leiomyomas: long-term results of a randomized comparative trial.
| العنوان: | Uterine artery embolization versus laparoscopic occlusion of uterine arteries for leiomyomas: long-term results of a randomized comparative trial. |
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| المؤلفون: | Hald K; Department of Obstetrics and Gynecology, Ullevål, Oslo University Hospital, Oslo, Norway. khald@online.no, Noreng HJ, Istre O, Kløw NE |
| المصدر: | Journal of vascular and interventional radiology : JVIR [J Vasc Interv Radiol] 2009 Oct; Vol. 20 (10), pp. 1303-10; quiz 1311. Date of Electronic Publication: 2009 Aug 26. |
| نوع المنشور: | Comparative Study; Journal Article; Randomized Controlled Trial |
| اللغة: | English |
| بيانات الدورية: | Publisher: Society of Cardiovascular and Interventional Radiology Country of Publication: United States NLM ID: 9203369 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-7732 (Electronic) Linking ISSN: 10510443 NLM ISO Abbreviation: J Vasc Interv Radiol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Reston, Va. : Society of Cardiovascular and Interventional Radiology, c1990- |
| مواضيع طبية MeSH: | Laparoscopy/*methods , Leiomyoma/*diagnosis , Leiomyoma/*therapy , Uterine Artery Embolization/*methods , Uterine Neoplasms/*diagnosis , Uterine Neoplasms/*therapy, Adult ; Female ; Humans ; Longitudinal Studies ; Treatment Outcome |
| مستخلص: | Purpose: To compare long-term symptom recurrence and 6-month magnetic resonance (MR) imaging results after two different treatments for uterine leiomyomas. Materials and Methods: Sixty-six women with uterine leiomyomas were randomized to undergo uterine artery embolization (UAE) or laparoscopic bilateral occlusion of uterine arteries. Contrast-enhanced MR imaging was performed before treatment and after 6 months. Results: Fifty-eight patients received treatment. Median follow-up time was 48 months (range, 8-73 months). Clinical failure and symptom recurrence occurred in 14 patients after laparoscopy (48%) and in five after UAE (17%; P = .02, log-rank test). Hysterectomy was performed in two patients after UAE (7%) and in eight after laparoscopy (28%; P = .041). Six-month MR imaging results were available for 26 patients treated with UAE and 22 treated with laparoscopy. The mean uterine volume was reduced by 51% (range, 16%-86%) after UAE treatment, compared with 33% (range, 6%-77%) after laparoscopy (P = .001). Complete leiomyoma infarction was seen in all 26 patients in the UAE group and in only five patients in the laparoscopy group (P < .001). Eleven patients experienced symptom recurrence later than 6 months. Uterine volume reduction at 6 months was 24% in this group, compared with 48% in the 37 patients with no recurrence (P = .004). Incomplete infarction of leiomyomas was seen in eight of the 11 cases of recurrence (73%) versus nine of 37 cases without recurrence (24%; P = .009). Conclusions: Recurrence rate was significantly lower after UAE than after laparoscopic treatment. Larger volume reduction and more complete devascularization of leiomyomas were found after UAE treatment and among patients with no recurrence. |
| تواريخ الأحداث: | Date Created: 20090829 Date Completed: 20100104 Latest Revision: 20091005 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1016/j.jvir.2009.07.022 |
| PMID: | 19713130 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1535-7732 |
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| DOI: | 10.1016/j.jvir.2009.07.022 |