دورية أكاديمية

Radiomodifying effect of organic grape juice supplementation on hematological parameters and organ weight in whole-body X-irradiation in rats.

التفاصيل البيبلوغرافية
العنوان: Radiomodifying effect of organic grape juice supplementation on hematological parameters and organ weight in whole-body X-irradiation in rats.
المؤلفون: Ramos de Andrade E; Centro de Ciências Naturais e Exatas, Ciências Biológicas, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil., Da Costa Escobar Piccoli J, Mânica da Cruz IB, Teixeira Rocha JB, Garzo E, Marina R, Mauriz JL, González P, Barrio JP
المصدر: Nutricion hospitalaria [Nutr Hosp] 2009 May-Jun; Vol. 24 (3), pp. 297-303.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Grupo Aran Country of Publication: Spain NLM ID: 9100365 Publication Model: Print Cited Medium: Print ISSN: 0212-1611 (Print) Linking ISSN: 02121611 NLM ISO Abbreviation: Nutr Hosp Subsets: MEDLINE
أسماء مطبوعة: Publication: 2016- : Madrid : Grupo Aran
Original Publication: Madrid : Jarpyo Editores,
مواضيع طبية MeSH: Beverages* , Dietary Supplements* , Vitis* , Whole-Body Irradiation*, Blood Cells/*drug effects , Blood Cells/*radiation effects , Organ Size/*drug effects , Organ Size/*radiation effects, Animals ; Male ; Rats ; Rats, Wistar
مستخلص: The aim of this study is testing black grape juice as a radiomodifier against whole body X-irradiation using an animal model. Sixteen male Wistar rats were divided into four groups where two were irradiated by X-rays from a 200 kV machine specially designed to biological samples. Animals were fed ad libitum and drank voluntarily 2-10 ml a day of grape juice or placebo (isocaloric glucose and fructose solution) for one week before and two weeks after 6 Gy X-irradiation when they were sacrificed. Results have shown a significant liver weight loss in irradiated placebo group only while grape juice one has presented no losses. Hematological analysis showed typical abnormalities for ionizing radiation exposure, including early leucopenia and anemia. The intake of grape juice induced an increase in granulocyte percent count.
تواريخ الأحداث: Date Created: 20090902 Date Completed: 20090930 Latest Revision: 20130702
رمز التحديث: 20240628
PMID: 19721902
قاعدة البيانات: MEDLINE