دورية أكاديمية

Human immunonodeficiency virus, hepatitis B virus and hepatitis C virus: sero-prevalence, co-infection and risk factors among prison inmates in Nasarawa State, Nigeria.

التفاصيل البيبلوغرافية
العنوان: Human immunonodeficiency virus, hepatitis B virus and hepatitis C virus: sero-prevalence, co-infection and risk factors among prison inmates in Nasarawa State, Nigeria.
المؤلفون: Adoga MP; Virology Department, Innovative Biotech Ltd, 1 Abdu Abubakar Street, GRA, P.O.Box 30, Keffi, Nigeria. madoga@innovativebiotechng.com, Banwat EB, Forbi JC, Nimzing L, Pam CR, Gyar SD, Agabi YA, Agwale SM
المصدر: Journal of infection in developing countries [J Infect Dev Ctries] 2009 Aug 30; Vol. 3 (7), pp. 539-47. Date of Electronic Publication: 2009 Aug 30.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Open Learning on Enteric Pathogens Country of Publication: Italy NLM ID: 101305410 Publication Model: Electronic Cited Medium: Internet ISSN: 1972-2680 (Electronic) Linking ISSN: 19722680 NLM ISO Abbreviation: J Infect Dev Ctries Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [Italy?] : Open Learning on Enteric Pathogens
مواضيع طبية MeSH: HIV Infections/*complications , HIV Infections/*epidemiology , Hepatitis B/*complications , Hepatitis B/*epidemiology , Hepatitis C/*complications , Hepatitis C/*epidemiology, Adolescent ; Adult ; Comorbidity ; Cross-Sectional Studies ; HIV Antibodies/blood ; Hepatitis B Surface Antigens/blood ; Hepatitis C Antibodies/blood ; Humans ; Immunoenzyme Techniques/methods ; Male ; Middle Aged ; Nigeria/epidemiology ; Prisoners ; Risk Factors ; Seroepidemiologic Studies ; Young Adult
مستخلص: Background: Published data on HIV, HBV, and HCV in correctional facilities in Nigeria is scarce. We set out to establish the seroprevalence, co-infection, and risk factors for these infections for the first time among prison inmates in Nasarawa State, Nigeria.
Methodology: In a cross-sectional study conducted between April and May, 2007, blood samples were collected from 300 male prisoners of a mean age of 29.2 years, in the state's four medium-security prisons (overall population: 587). Prior to the study, ethical clearance and informed consent were obtained and structured questionnaires were administered. Samples were analyzed for HIV, HBsAg, and HCV using anti-HIV 1+2-EIA-avicenna, Shantest-HBsAg ELISA, and anti-HCV-EIA-avicenna, respectively. Specimens initially reactive for HIV were retested with vironostika microelisa. Data were analyzed using SPSS version 13.0. P values < or = 0.05 were considered significant.
Results: Of the 300 subjects, 54 (18.0 %), 69 (23.0 %), and 37 (12.3 %) tested positive for HIV, HBV, and HCV, respectively. Co-infections were eight (2.7 %) for HIV/HBV and two (0.7 %) for HBV/HCV. Those aged 21-26 years were more likely to be infected with HIV and HBV, while those aged 33-38 years had the highest HCV infection. Associated risk factors included duration in prison, previous incarceration (for HIV, HBV and HCV), intra-prison anal sex, multiple sex partners (for HIV and HBV), ignorance of transmission modes, blood transfusion, and alcohol consumption (for HBV and HCV). No inmate injected drugs.
Conclusions: The overall outcome represents the need for prison-focused intervention initiatives in Nigeria. Injected drug use is an unlikely major transmission mode among Nigerian inmates.
المشرفين على المادة: 0 (HIV Antibodies)
0 (Hepatitis B Surface Antigens)
0 (Hepatitis C Antibodies)
تواريخ الأحداث: Date Created: 20090919 Date Completed: 20091130 Latest Revision: 20220321
رمز التحديث: 20231215
DOI: 10.3855/jidc.472
PMID: 19762972
قاعدة البيانات: MEDLINE
الوصف
تدمد:1972-2680
DOI:10.3855/jidc.472