دورية أكاديمية
Antimicrobial resistant profile of Streptococcus pneumoniae isolated from the nasopharynx of secondary school students in Jos, Nigeria.
| العنوان: | Antimicrobial resistant profile of Streptococcus pneumoniae isolated from the nasopharynx of secondary school students in Jos, Nigeria. |
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| المؤلفون: | Kandakai-Olukemi YT; Department of Medical Microbiology, Faculty of Medical Sciences, University of Jos, P.M.B. 2084, Jos, Nigeria. Kandakait@yahoo.com, Dido MS |
| المصدر: | Annals of African medicine [Ann Afr Med] 2009 Jan-Mar; Vol. 8 (1), pp. 10-3. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Medknow Publications Country of Publication: India NLM ID: 101231417 Publication Model: Print Cited Medium: Internet ISSN: 0975-5764 (Electronic) Linking ISSN: 09755764 NLM ISO Abbreviation: Ann Afr Med Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Mumbai, India : Medknow Publications Original Publication: Sokoto, Nigeria : [Zaria, Nigeria?] : Usmanu Danfodiyo University Teaching Hospital ; Annals of African Medicine Society |
| مواضيع طبية MeSH: | Drug Resistance, Multiple, Bacterial*, Anti-Bacterial Agents/*pharmacology , Nasopharynx/*microbiology , Pneumococcal Infections/*drug therapy , Streptococcus pneumoniae/*drug effects, Adolescent ; Adult ; Carrier State/microbiology ; Female ; Humans ; Male ; Microbial Sensitivity Tests ; Nigeria/epidemiology ; Penicillin Resistance ; Pneumococcal Infections/epidemiology ; Pneumococcal Infections/microbiology ; Population Surveillance ; Schools ; Streptococcus pneumoniae/isolation & purification ; Young Adult |
| مستخلص: | Background: Antimicrobial resistance in Streptococcus pneumoniae has compromised the effectiveness of therapy for pneumococcal diseases and asymptomatic nasopharyngeal carriers play an important role in transmission of resistant strains. Method: Eighty-eight volunteer students attending 2 secondary schools in Jos, Nigeria were involved in this study to determine the antimicrobial resistant profile of Streptococcus pneumoniae isolated from the nasopharynx. The study population consisted of males and females between the ages of 15-25 years. Nasopharyngeal swab samples were analyzed for the presence of S. pneumoniae using standard bacteriological methods. The isolates were subjected to antimicrobial susceptibility testing using the disc diffusion method. Results: S. pneumoniae was isolated from 37 (42.04%) of the 88 samples. Isolates showed the highest resistance of 12 (32.43%) to erythromycin and lowest resistance of 4 (10.81%) to ciprofloxacin. The resistance profiles for the 26 (70.27%) penicillin-sensitive and 11 (29.72%) penicillin-resistant isolates were similar. Both exhibited varying degrees of resistance to several groups of antimicrobials. However, isolates found to be resistant to penicillin showed a higher degree of resistance to other antimicrobial agents. Conclusion: This study has shown that some secondary school students are carriers of multiple antibiotic-resistant S. pneumoniae. |
| المشرفين على المادة: | 0 (Anti-Bacterial Agents) |
| تواريخ الأحداث: | Date Created: 20090919 Date Completed: 20100526 Latest Revision: 20191111 |
| رمز التحديث: | 20240628 |
| DOI: | 10.4103/1596-3519.55757 |
| PMID: | 19763000 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0975-5764 |
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| DOI: | 10.4103/1596-3519.55757 |