دورية أكاديمية
Assessment of breast lesions with diffusion-weighted MRI: comparing the use of different b values.
| العنوان: | Assessment of breast lesions with diffusion-weighted MRI: comparing the use of different b values. |
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| المؤلفون: | Pereira FP; Clínica de Diagnóstico Por Imagem, Rua Ataulfo de Paiva, 669, 2nd floor, Leblon, Rio de Janeiro, RJ, Brazil, 22649-900. fephila@gmail.com, Martins G, Figueiredo E, Domingues MN, Domingues RC, da Fonseca LM, Gasparetto EL |
| المصدر: | AJR. American journal of roentgenology [AJR Am J Roentgenol] 2009 Oct; Vol. 193 (4), pp. 1030-5. |
| نوع المنشور: | Comparative Study; Evaluation Study; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Roentgen Ray Society Country of Publication: United States NLM ID: 7708173 Publication Model: Print Cited Medium: Internet ISSN: 1546-3141 (Electronic) Linking ISSN: 0361803X NLM ISO Abbreviation: AJR Am J Roentgenol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2004-> : Leesburg, VA : American Roentgen Ray Society Original Publication: Springfield, Ill., Thomas. |
| مواضيع طبية MeSH: | Algorithms*, Breast Neoplasms/*diagnosis , Diffusion Magnetic Resonance Imaging/*methods , Image Enhancement/*methods , Image Interpretation, Computer-Assisted/*methods, Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Middle Aged ; Reproducibility of Results ; Sensitivity and Specificity ; Young Adult |
| مستخلص: | Objective: Our purpose was to study the utility of diffusion-weighted MRI in differentiating benign from malignant breast lesions by assessing the best b values. Subjects and Methods: Forty-five women (mean age, 46.1 years) with 52 focal mass breast lesions underwent diffusion-weighted imaging with different b values. The apparent diffusion coefficient (ADC) value of each lesion was calculated from the ADC maps done using five b values (0, 250, 500, 750, and 1,000 s/mm(2)) and using b values of 0 s/mm(2) with each other b value separately (0 and 250 s/mm(2), 0 and 500 s/mm(2), 0 and 750 s/mm(2), 0 and 1,000 s/mm(2)). The mean ADC values were correlated with imaging findings and histopathologic diagnoses. The cutoff ADC value, sensitivity, and specificity of diffusion-weighted imaging to differentiate benign and malignant lesions were calculated in all b value combinations. A p value of < 0.05 was considered statistically significant. Results: The mean ADC value was significantly lower for malignant lesions compared to benign lesions (p < 0.0001) in all b value combinations. No statistical difference was seen between the ADC obtained from different b value combinations (p = 0.2581) in the differentiation between benign and malignant lesions. The ADC calculated from b 0 and 750 s/mm(2) was slightly better than the other b value combinations, showing a sensitivity of 92.3% and a specificity of 96.2%. Conclusion: Diffusion-weighted imaging is a potential resource as a coadjutant of MRI in the differentiation between benign and malignant lesions. Such imaging can be performed without a significant increase in examination time, especially because it can be done with lower b values. |
| التعليقات: | Erratum in: AJR Am J Roentgenol. 2011 Feb;196(2):477. |
| تواريخ الأحداث: | Date Created: 20090923 Date Completed: 20091014 Latest Revision: 20220409 |
| رمز التحديث: | 20231215 |
| DOI: | 10.2214/AJR.09.2522 |
| PMID: | 19770326 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1546-3141 |
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| DOI: | 10.2214/AJR.09.2522 |