دورية أكاديمية

Is routine antenatal screening for syphilis in Nigeria still justified clinically and economically?

التفاصيل البيبلوغرافية
العنوان: Is routine antenatal screening for syphilis in Nigeria still justified clinically and economically?
المؤلفون: Bukar M; Department of Obstetrics & Gynaecology, University of Maiduguri Teaching Hospital, PO Box 1414, Maiduguri, Borno State, Nigeria. mbbukar07@yahoo.com, Audu BM, Takai UI, Ajayi BB, Kullima AA
المصدر: Saudi medical journal [Saudi Med J] 2009 Oct; Vol. 30 (10), pp. 1311-5.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Medical Services Department, Saudi Arabian Armed Forces, Ministry Of Defence And Aviation Country of Publication: Saudi Arabia NLM ID: 7909441 Publication Model: Print Cited Medium: Internet ISSN: 0379-5284 (Print) Linking ISSN: 03795284 NLM ISO Abbreviation: Saudi Med J Subsets: MEDLINE
أسماء مطبوعة: Publication: Riyadh : Medical Services Department, Saudi Arabian Armed Forces, Ministry Of Defence And Aviation
Original Publication: Riyadh, Saudi Arabia, Riyadh Al-Kharj Hospital Programme.
مواضيع طبية MeSH: Diagnostic Tests, Routine/*statistics & numerical data , Mass Screening/*statistics & numerical data , Syphilis/*diagnosis, Cardiolipins/analysis ; Cholesterol/analysis ; Diagnostic Tests, Routine/standards ; Female ; Hemagglutination Tests ; Humans ; Nigeria/epidemiology ; Phosphatidylcholines/analysis ; Pregnancy ; Pregnancy Complications, Infectious/diagnosis ; Pregnancy Complications, Infectious/economics ; Pregnancy Complications, Infectious/epidemiology ; Prenatal Care/economics ; Prenatal Care/methods ; Prenatal Diagnosis/statistics & numerical data ; Prevalence ; Retrospective Studies ; Seroepidemiologic Studies ; Syphilis/economics ; Syphilis/epidemiology ; Treponema pallidum/isolation & purification
مستخلص: Objective: To determine the seroprevalence and cost effectiveness of antenatal syphilis screening at the University of Maiduguri Teaching Hospital (UMTH), Maiduguri, Nigeria.
Methods: A retrospective chart analysis of venereal disease research laboratory (VDRL) results among pregnant women at the UMTH, Maiduguri, Nigeria, during a 10-year period (from 1st January 1999 to 31st December 2008) was undertaken.
Results: A total of 18,712 women registered for antenatal care during the study period. Of these, 18,101 had serological screening for syphilis. Only 12 of the 18,101 screened were seropositive by VDRL, 9 (75%) were confirmed by Treponema pallidum hemagglutination assay (TPHA), giving a seroprevalence rate of 0.05%. Three (25%) were biological false-positive. The peak age-specific incidence of 0.02% was in the 20-24 year-age group. There was zero prevalence in the age groups 15-19 and >40 years. There was no case of congenital syphilis seen. The cost for VDRL testing per patient in UMTH is US$2. The total amount of money spent on VDRL tests over the study period was US$37,424.
Conclusion: The seroprevalence rate of syphilis is extremely low in this study. This calls for a review of the policy of routine antenatal serology screening for syphilis in Maiduguri, Nigeria.
التعليقات: Comment in: Saudi Med J. 2011 Jan;32(1):92-3. (PMID: 21212929)
المشرفين على المادة: 0 (Cardiolipins)
0 (Phosphatidylcholines)
0 (VDRL antigen)
97C5T2UQ7J (Cholesterol)
تواريخ الأحداث: Date Created: 20091020 Date Completed: 20100113 Latest Revision: 20220409
رمز التحديث: 20221213
PMID: 19838440
قاعدة البيانات: MEDLINE