دورية أكاديمية
[The 24 May, 2009 isolation of the first A/IIV-Moscow/01/2009 (H1N1)swl strain similar to swine A(H1N1) influenza virus from the first Moscow case detected on May 21, 2009, and its deposit in the state collection of viruses (SCV No. 2452 dated May 24, 2009)].
| العنوان: | [The 24 May, 2009 isolation of the first A/IIV-Moscow/01/2009 (H1N1)swl strain similar to swine A(H1N1) influenza virus from the first Moscow case detected on May 21, 2009, and its deposit in the state collection of viruses (SCV No. 2452 dated May 24, 2009)]. |
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| المؤلفون: | L'vov DK, Burtseva EI, Prilipov AG, Bazarova MV, Kolobukhina LV, Merkulova LN, Malyshev NA, Deriabin PG, Fediakina IT, Sadykova GK, Usachev EV, Shchelkanov MIu, Shevchenko ES, Trushakova SV, Ivanova VT, Beliakova NV, Oskerko TA, Aliper TI |
| المصدر: | Voprosy virusologii [Vopr Virusol] 2009 Sep-Oct; Vol. 54 (5), pp. 10-4. |
| نوع المنشور: | Journal Article |
| اللغة: | Russian |
| بيانات الدورية: | Publisher: FBUN T︠S︡NII Ėpidemiologii Rospotrebnadzora Country of Publication: Russia (Federation) NLM ID: 0417337 Publication Model: Print Cited Medium: Print ISSN: 0507-4088 (Print) Linking ISSN: 05074088 NLM ISO Abbreviation: Vopr Virusol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Moskva : FBUN T︠S︡NII Ėpidemiologii Rospotrebnadzora Original Publication: Moskva : Ministerstvo zdravookhranenii︠a︡ SSSR |
| مواضيع طبية MeSH: | Influenza A Virus, H1N1 Subtype/*isolation & purification , Influenza, Human/*epidemiology , Influenza, Human/*virology, Amino Acid Substitution ; Animals ; Antiviral Agents/pharmacology ; Cell Line ; Chick Embryo ; Drug Resistance, Viral ; Genome, Viral ; Humans ; Indoles/pharmacology ; Influenza A Virus, H1N1 Subtype/drug effects ; Influenza A Virus, H1N1 Subtype/genetics ; Microbial Sensitivity Tests ; Molecular Sequence Data ; Moscow/epidemiology ; Neuraminidase/genetics ; Oseltamivir/pharmacology ; Ribavirin/pharmacology ; Rimantadine/pharmacology ; Travel ; Viral Proteins/genetics |
| مستخلص: | The paper presents the results of the first isolation of the new influenza virus in Moscow and the Russian Federation, which was similar to the swine A/IIV-Moscow/01/2009(H1N1)swl strain isolated on May 24, 2009 from a Russian arrived in Moscow from the USA on May 19, 2009. The antigenic, biological, and molecular genetic properties of this virus were studied. The virus was isolated on MDCK and chick embryos, the hemagglutination titers being 1:8-1:16 AE; the infectious titers being 6.51g of the tissue cytopathogenic infective dose (TCID50) and 7.01g of the common infective dose (CID50). The virus was sensitive to arbidol, ribavirin, oseltamivir, and resistant to rimantadine. The complete virus genome was sequenced; the data were accepted to the Gen Bank on May 28, 2009 under GQ219584-GQ219590 and GQ202724. The significant gene substitution of neuraminidase Asp for Gly in position 451, which has been undetectable in any other strain published in the Gen Bank by the present time is unique only to A/IIV-Moscow/01/2009 (H1N1)swl. The virus has been deposited in the State Collection of Viruses, D. I. Ivanovsky Institute of Virology, Russian Academy of Medical Sciences, under No. 2452 dated May 24, 2009. |
| سلسلة جزيئية: | GENBANK GQ202724; GQ219584; GQ219585; GQ219586; GQ219587; GQ219588; GQ219589; GQ219590 |
| المشرفين على المادة: | 0 (Antiviral Agents) 0 (Indoles) 0 (Viral Proteins) 0T2EF4JQTU (Rimantadine) 20O93L6F9H (Oseltamivir) 49717AWG6K (Ribavirin) 93M09WW4RU (umifenovir) EC 3.2.1.18 (Neuraminidase) |
| تواريخ الأحداث: | Date Created: 20091104 Date Completed: 20091217 Latest Revision: 20201126 |
| رمز التحديث: | 20231215 |
| PMID: | 19882896 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0507-4088 |
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