دورية أكاديمية
Traumatic brain injury: neuroprotective anaesthetic techniques, an update.
| العنوان: | Traumatic brain injury: neuroprotective anaesthetic techniques, an update. |
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| المؤلفون: | Tawfeeq NA; Department of Anaesthesia, King Abdulaziz Medical City, Riyadh, Saudi Arabia., Halawani MM, Al-Faridi K, Aal-Shaya WA, Taha WS |
| المصدر: | Injury [Injury] 2009 Nov; Vol. 40 Suppl 4, pp. S75-81. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0226040 Publication Model: Print Cited Medium: Internet ISSN: 1879-0267 (Electronic) Linking ISSN: 00201383 NLM ISO Abbreviation: Injury Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2002->: Amsterdam : Elsevier Original Publication: Bristol, Wright. |
| مواضيع طبية MeSH: | Brain Injuries/*therapy , Craniocerebral Trauma/*complications , Hypoxia-Ischemia, Brain/*therapy , Neuroprotective Agents/*pharmacology , Perioperative Care/*methods, Adolescent ; Adult ; Brain Injuries/complications ; Brain Injuries/physiopathology ; Cell Death/drug effects ; Cell Death/physiology ; Central Nervous System Depressants/therapeutic use ; Craniocerebral Trauma/therapy ; Cyclosporine/pharmacology ; Dexmedetomidine/pharmacology ; Erythropoietin/pharmacology ; Humans ; Hypothermia, Induced ; Hypoxia-Ischemia, Brain/etiology ; Intracranial Hypotension/etiology ; Intracranial Hypotension/therapy ; Isoflurane/pharmacology ; Middle Aged ; Neuroprotective Agents/therapeutic use ; Nitrous Oxide/therapeutic use ; Propofol/pharmacology ; Resuscitation/methods ; Saline Solution, Hypertonic/therapeutic use ; Xenon/pharmacology ; Young Adult |
| مستخلص: | Traumatic brain injuries remain an area of great challenge to both neurosurgeons and neuroanaesthesiologists. The management of these injuries starts at the scene of the accident. However, strategies for preventing secondary brain injury and its sequelae are continuing to evolve. These strategies include the use of pharmacological and nonpharmacological techniques. Preventing hypoxia and the use of hypertonic saline have been shown to have favourable results on the outcome of these injuries. The use of isoflurane has been shown to have a neuronprotective effect. Propofol is thought to be the future drug of choice because of its neuroprotective properties, although these still need to be further proven through research. In this review an understanding of the pathophysiology of traumatic brain injury will be outlined in order to understand the effects of pharmacological and nonpharmacological agents on secondary brain injury. |
| Number of References: | 47 |
| المشرفين على المادة: | 0 (Central Nervous System Depressants) 0 (Neuroprotective Agents) 0 (Saline Solution, Hypertonic) 11096-26-7 (Erythropoietin) 3H3U766W84 (Xenon) 67VB76HONO (Dexmedetomidine) 83HN0GTJ6D (Cyclosporine) CYS9AKD70P (Isoflurane) K50XQU1029 (Nitrous Oxide) YI7VU623SF (Propofol) |
| تواريخ الأحداث: | Date Created: 20091110 Date Completed: 20100826 Latest Revision: 20131121 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/j.injury.2009.10.040 |
| PMID: | 19895957 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1879-0267 |
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| DOI: | 10.1016/j.injury.2009.10.040 |