دورية أكاديمية
[Evaluation of the effectiveness and safety of synthetic colloid solutions in the treatment of severe abdominal sepsis: a randomized comparative study].
| العنوان: | [Evaluation of the effectiveness and safety of synthetic colloid solutions in the treatment of severe abdominal sepsis: a randomized comparative study]. |
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| المؤلفون: | Protsenko DN, Leĭderman IN, Grigor'ev EV, Kokarev EA, Levit AL, Gel'fand BR |
| المصدر: | Anesteziologiia i reanimatologiia [Anesteziol Reanimatol] 2009 Sep-Oct (5), pp. 9-13. |
| نوع المنشور: | Comparative Study; English Abstract; Journal Article; Multicenter Study; Randomized Controlled Trial |
| اللغة: | Russian |
| بيانات الدورية: | Publisher: Meditsina Country of Publication: Russia (Federation) NLM ID: 7705399 Publication Model: Print Cited Medium: Print ISSN: 0201-7563 (Print) Linking ISSN: 02017563 NLM ISO Abbreviation: Anesteziol Reanimatol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Moskva : Meditsina Original Publication: Moskva, Meditsina. |
| مواضيع طبية MeSH: | Abdomen*, Fluid Therapy/*methods , Gelatin/*therapeutic use , Hydroxyethyl Starch Derivatives/*therapeutic use , Hypovolemia/*prevention & control , Plasma Substitutes/*therapeutic use , Shock, Septic/*therapy , Succinates/*therapeutic use, APACHE ; Adolescent ; Adult ; Gelatin/administration & dosage ; Hemodynamics ; Humans ; Hydroxyethyl Starch Derivatives/administration & dosage ; Hydroxyethyl Starch Derivatives/analogs & derivatives ; Hypovolemia/etiology ; Middle Aged ; Multiple Organ Failure/complications ; Multiple Organ Failure/physiopathology ; Multiple Organ Failure/therapy ; Peritonitis/complications ; Peritonitis/physiopathology ; Peritonitis/therapy ; Plasma Substitutes/administration & dosage ; Shock, Septic/complications ; Shock, Septic/physiopathology ; Succinates/administration & dosage ; Treatment Outcome ; Young Adult |
| مستخلص: | Infusion therapy, surgical debridement of an infection focus, and antimicrobial therapy are basic treatments for severe sepsis. At the same time there are no uniform guidelines on how to choose fluids for infusion therapy. The results of individual studies serve as the basis for refusing the use of synthetic colloid agents in the therapy of severe sepsis. The presented multicenter, randomized comparative study has evaluated different synthetic colloid solutions in early targeted therapy for severe sepsis. Evidence is provided for the identical effectiveness of the compared solutions in correcting hypovolemia and stabilizing hemodynamics in patients with severe sepsis and septic shock. |
| المشرفين على المادة: | 0 (Hydroxyethyl Starch Derivatives) 0 (Plasma Substitutes) 0 (Succinates) 39340-57-3 (succinylated gelatin) 9000-70-8 (Gelatin) |
| تواريخ الأحداث: | Date Created: 20091127 Date Completed: 20100804 Latest Revision: 20131121 |
| رمز التحديث: | 20221213 |
| PMID: | 19938709 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0201-7563 |
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