دورية أكاديمية
أعرض في EDS

Non-soy legume consumption lowers cholesterol levels: a meta-analysis of randomized controlled trials.

التفاصيل البيبلوغرافية
العنوان: Non-soy legume consumption lowers cholesterol levels: a meta-analysis of randomized controlled trials.
المؤلفون: Bazzano LA; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA. lbazzano@tulane.edu, Thompson AM, Tees MT, Nguyen CH, Winham DM
المصدر: Nutrition, metabolism, and cardiovascular diseases : NMCD [Nutr Metab Cardiovasc Dis] 2011 Feb; Vol. 21 (2), pp. 94-103. Date of Electronic Publication: 2009 Nov 25.
نوع المنشور: Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9111474 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1590-3729 (Electronic) Linking ISSN: 09394753 NLM ISO Abbreviation: Nutr Metab Cardiovasc Dis Subsets: MEDLINE
أسماء مطبوعة: Publication: 2005- : Amsterdam : Elsevier
Original Publication: [Heidelberg] : Springer International, c1991-
مواضيع طبية MeSH: Cholesterol, HDL/*blood , Cholesterol, LDL/*blood , Fabaceae/*chemistry , Plant Proteins, Dietary/*administration & dosage, Adolescent ; Adult ; Aged ; Cardiovascular Diseases/diet therapy ; Confidence Intervals ; Diet ; Female ; Humans ; Hypercholesterolemia/diet therapy ; Isoflavones/pharmacology ; Linear Models ; Male ; Middle Aged ; Randomized Controlled Trials as Topic ; Triglycerides/blood ; Young Adult
مستخلص: Background and Aims: Studies evaluating the effect of legume consumption on cholesterol have focused on soybeans, however non-soy legumes, such as a variety of beans, peas, and some seeds, are commonly consumed in Western countries. We conducted a meta-analysis of randomized controlled trials evaluating the effects of non-soy legume consumption on blood lipids.
Methods and Results: Studies were retrieved by searching MEDLINE (from January 1966 through July 2009), EMBASE (from January 1980 to July 2009), and the Cochrane Collaboration's Central Register of Controlled Clinical Trials using the following terms as medical subject headings and keywords: fabaceae not soybeans not isoflavones and diet or dietary fiber and cholesterol or hypercholesterolemia or triglycerides or cardiovascular diseases. Bibliographies of all retrieved articles were also searched. From 140 relevant reports, 10 randomized clinical trials were selected which compared a non-soy legume diet to control, had a minimum duration of 3 weeks, and reported blood lipid changes during intervention and control. Data on sample size, participant characteristics, study design, intervention methods, duration, and treatment results were independently abstracted by 2 investigators using a standardized protocol. Data from 10 trials representing 268 participants were examined using a random-effects model. Pooled mean net change in total cholesterol for those treated with a legume diet compared to control was -11.8 mg/dL (95% confidence interval [CI], -16.1 to -7.5); mean net change in low-density lipoprotein cholesterol was -8.0mg/dL (95% CI, -11.4 to -4.6).
Conclusion: These results indicate that a diet rich in legumes other than soy decreases total and LDL cholesterol.
(Copyright © 2009 Elsevier B.V. All rights reserved.)
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معلومات مُعتمدة: P20 RR017659 United States RR NCRR NIH HHS; P20 RR017659-077420 United States RR NCRR NIH HHS; 2P20RR017659-06 United States RR NCRR NIH HHS
المشرفين على المادة: 0 (Cholesterol, HDL)
0 (Cholesterol, LDL)
0 (Isoflavones)
0 (Plant Proteins, Dietary)
0 (Triglycerides)
تواريخ الأحداث: Date Created: 20091127 Date Completed: 20110519 Latest Revision: 20211020
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC2888631
DOI: 10.1016/j.numecd.2009.08.012
PMID: 19939654
قاعدة البيانات: MEDLINE
الوصف
تدمد:1590-3729
DOI:10.1016/j.numecd.2009.08.012