دورية أكاديمية
[A meta-analysis of nasal intermittent positive pressure ventilation in treatment of respiratory distress syndrome in premature infants].
| العنوان: | [A meta-analysis of nasal intermittent positive pressure ventilation in treatment of respiratory distress syndrome in premature infants]. |
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| المؤلفون: | Cui YP; Department of Pediatrics, Peking University Third Hospital and School of Public Health, Peking University, Beijing 100083, China., Tong XM, Ye HM, Wang B, Tang YN |
| المصدر: | Zhonghua er ke za zhi = Chinese journal of pediatrics [Zhonghua Er Ke Za Zhi] 2009 Jul; Vol. 47 (7), pp. 532-6. |
| نوع المنشور: | Journal Article; Meta-Analysis; Systematic Review |
| اللغة: | Chinese |
| بيانات الدورية: | Publisher: Chinese Medical Association Country of Publication: China NLM ID: 0417427 Publication Model: Print Cited Medium: Print ISSN: 0578-1310 (Print) Linking ISSN: 05781310 NLM ISO Abbreviation: Zhonghua Er Ke Za Zhi Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Beijing : Chinese Medical Association, 1950 |
| مواضيع طبية MeSH: | Infant, Premature* , Intermittent Positive-Pressure Ventilation*, Respiratory Distress Syndrome, Newborn/*therapy, Humans ; Infant, Newborn |
| مستخلص: | Objective: To assess the efficacy of nasal intermittent positive pressure ventilation (NIPPV) in treatment of respiratory distress syndrome (RDS) in premature infants. Methods: According to the requirements of Cochrane systematic review, a thorough literature search was performed among PubMed (1977-2008), Embase (1989-2008), OVID, Cochrane (2008), Chinese Digital Hospital Library (www.chkd.cnki.net) and Chinese Biomedical Literature Disk Database (CBMdisc). Quality assessments of clinical trials were carried out. Randomized controlled trials (RCTs) with NIPPV and RDS were enrolled, and Revman 4.2 software was used for meta-analysis. The trials were analyzed using relative risk (RR) for dichotomous data, weighted mean difference (WMD) were used for continuous data, both kind of data were expressed by 95% confidence intervals (95% CI). For homogenous data (P> or =0.10), fixed effects model was calculated, for heterogeneity data (P<0.10), random effects model was calculated. Results: Five RCTs involving 284 premature infants diagnosed as respiratory distress syndrome (RDS) were included. Three studies comparing NIPPV with nasal continuous positive airway pressure (NCPAP) in the postextubation period, the extubation failure rate was 8.34% vs 40.79% in NIPPV group and NCPAP group, the NIPPV group had significantly lower extubation failure rates [RR 0.21 (95% CI: 0.10-0.45; P<0.001)]. Two of the above-mentioned three studies analyzed bronchopulmonary dysplasia (BPD) rates, the incidence of BPD was 39.34% vs 54.39% in NIPPV group and NCPAP group, the NIPPV group had a trend towards lower BPD rates, but this did not reach statistical significance [RR 0.73 (95% CI: 0.49-1.07; P=0.11)]. NIPPV was used as primary mode in two studies, one compared with conventional ventilation (CV), which detected that the NIPPV group had significantly lower BPD rates (10% vs. 33.33%, P=0.04); the other compared with NCPAP, which also showed that NIPPV group had significantly lower BPD rates (2.33% vs. 17.07%, P=0.03). Conclusion: The primary mode NIPPV was found to be feasible as a method of ventilation in preterm infants with RDS, and was associated with a decreased incidence of BPD. In the postextubation period, NIPPV is more effective in preventing failure of extubation than NCPAP. |
| تواريخ الأحداث: | Date Created: 20091203 Date Completed: 20101202 Latest Revision: 20181201 |
| رمز التحديث: | 20240628 |
| PMID: | 19951518 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0578-1310 |
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