التفاصيل البيبلوغرافية
| العنوان: |
Parathyroid cancer as rare cause of primary hyperparathyroidism. Case report and review of the literature. |
| المؤلفون: |
Troilo VL; Department of Clinical Methodology and Medical and Surgical Technologies, University of Bari, Bari, Italy., D'Eredità G, Fischetti F, Berardi T |
| المصدر: |
Il Giornale di chirurgia [G Chir] 2009 Oct; Vol. 30 (10), pp. 432-6. |
| نوع المنشور: |
Case Reports; Journal Article; Review |
| اللغة: |
English |
| بيانات الدورية: |
Publisher: CIC edizioni internazionali Country of Publication: Italy NLM ID: 9011768 Publication Model: Print Cited Medium: Print ISSN: 0391-9005 (Print) Linking ISSN: 03919005 NLM ISO Abbreviation: G Chir Subsets: MEDLINE |
| أسماء مطبوعة: |
Original Publication: Roma : CIC edizioni internazionali, |
| مواضيع طبية MeSH: |
Carcinoma/*complications , Hyperparathyroidism, Primary/*etiology , Parathyroid Neoplasms/*complications, Female ; Humans ; Middle Aged |
| مستخلص: |
Primary hyperparathyroidism (PHPT) due to parathyroid carcinoma is rare, and affects more frequently women in their 4th-5th decades of life. Parathyroid cancer (PC) accounts for 0.5% up to 5% of the patients with primary hyperparathyroidism (PHPT). Diagnosis of PC is not easy, and a lot of patients with PHPT receive no pre-operative or intra-operative diagnosis of malignancy. Most of PC are hyperfunctioning, with marked serum PTH levels, and symptoms occurs more frequently than in benign disease. We report the case of a 52 years old woman that underwent a single parathyroidectomy for hyperfunctioning gland. Histological examination revealed carcinoma. Parathyroid carcinoma is rare and surgery represent the only curative approach, although there can be a local recurrence of the disease. A pre-operative diagnosis is not easy, and many features that suggest the diagnosis of malignancy are controversial. According to the literature, we think that the cure of the parathyroid cancer is difficult to achieve. After two years of follow- up, our patient is in good conditions and has no evidence of disease. A careful follow up is of primary importance to diagnose the local recurrence of disease and perform a second surgical treatment, to achieve the control of hypercalcemia, which causes severe metabolic alterations and visceral lesions until the death. |
| Number of References: |
13 |
| تواريخ الأحداث: |
Date Created: 20091204 Date Completed: 20100803 Latest Revision: 20091203 |
| رمز التحديث: |
20221213 |
| PMID: |
19954585 |
| قاعدة البيانات: |
MEDLINE |
