دورية أكاديمية

The clinical value of chloral hydrate in the routine electroencephalogram.

التفاصيل البيبلوغرافية
العنوان: The clinical value of chloral hydrate in the routine electroencephalogram.
المؤلفون: Britton JW; Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA. britton.jeffrey@mayo.edu, Kosa SC
المصدر: Epilepsy research [Epilepsy Res] 2010 Feb; Vol. 88 (2-3), pp. 215-20. Date of Electronic Publication: 2009 Dec 23.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8703089 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-6844 (Electronic) Linking ISSN: 09201211 NLM ISO Abbreviation: Epilepsy Res Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Amsterdam : Elsevier Science Publishers, c1987-
مواضيع طبية MeSH: Chloral Hydrate*, Electroencephalography/*methods , Epilepsy/*diagnosis, Adult ; Chi-Square Distribution ; Child ; Conscious Sedation ; Female ; Humans ; Hypnotics and Sedatives ; Male ; Middle Aged ; Retrospective Studies
مستخلص: Purpose: To evaluate the diagnostic yield and clinical impact of chloral hydrate (CH) in the routine EEG.
Methods: The EEG results and records of all patients receiving CH during routine EEG (CH-EEG) at Mayo Clinic Rochester between 4/1/07 and 9/30/07 (n=216 total; 148 adults) were reviewed for clinical indication, presence of epileptiform abnormalities and EEG duration. The results were compared to an equivalent number of consecutive EEGs performed without CH over the same time period (non-CH-EEGs). The clinical impact of the CH-EEG findings was evaluated by evaluating resulting clinical decisions made in the medical record. Chi-squared analysis was performed for discontinuous data, Student's t-test for continuous data.
Results: The proportion of EEGs with sleep-specific epileptiform abnormalities (SSEAs) was not statistically different (7.8% CH-EEG vs. 10.5% non-CH-EEG, p=0.34). CH was ordered more often by non-epileptologists than epileptologists (57% vs. 35%, p=0.0004). The mean acquisition time was greater for CH-EEGs (66.9min vs. 55.1min; p<<0.001). CH-EEGs resulted in a change in clinical management in 5/216 (2.3%).
Discussion: Compared to non-CH-EEGs, CH-EEGs were no more likely to show SSEAs, prolonged the acquisition time, and were associated with changes in clinical care in <3%. Routine use of CH in outpatient EEG is not strongly supported by these data.
المشرفين على المادة: 0 (Hypnotics and Sedatives)
418M5916WG (Chloral Hydrate)
تواريخ الأحداث: Date Created: 20091225 Date Completed: 20100503 Latest Revision: 20151119
رمز التحديث: 20231215
DOI: 10.1016/j.eplepsyres.2009.11.012
PMID: 20031374
قاعدة البيانات: MEDLINE
الوصف
تدمد:1872-6844
DOI:10.1016/j.eplepsyres.2009.11.012