دورية أكاديمية
Ganjam virus.
العنوان: | Ganjam virus. |
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المؤلفون: | Sudeep AB; Microbial Containment Complex, National Institute of Virology (ICMR), Pune, India. sudeepab@icmr.org.in, Jadi RS, Mishra AC |
المصدر: | The Indian journal of medical research [Indian J Med Res] 2009 Nov; Vol. 130 (5), pp. 514-9. |
نوع المنشور: | Journal Article; Review |
اللغة: | English |
بيانات الدورية: | Publisher: Medknow Country of Publication: India NLM ID: 0374701 Publication Model: Print Cited Medium: Internet ISSN: 0971-5916 (Print) Linking ISSN: 09715916 NLM ISO Abbreviation: Indian J Med Res Subsets: MEDLINE |
أسماء مطبوعة: | Publication: <2011- > : Mumbai : Medknow Original Publication: New Delhi : Council Of Medical Research |
مواضيع طبية MeSH: | Nairobi sheep disease virus/*pathogenicity, Animals ; Bunyaviridae Infections/transmission ; Bunyaviridae Infections/virology ; Female ; Goats ; Humans ; India ; Male ; Mice ; Nairobi Sheep Disease/virology ; Nairobi sheep disease virus/genetics ; Nairobi sheep disease virus/isolation & purification ; Nairobi sheep disease virus/physiology ; Sheep ; Ticks/virology ; Virus Replication ; Zoonoses/transmission ; Zoonoses/virology |
مستخلص: | Ganjam virus (GANV), a member of genus Nairovirus of family Bunyavirdae is of considerable veterinary importance in India. Though, predominantly tick borne, GANV was also isolated from mosquitoes, man and sheep. Neutralizing and complement fixing antibodies to GANV have been detected in animal and human sera collected from different parts of the country. Thirty three strains of GANV have been isolated from India, mainly from Haemaphysalis ticks. The virus replicated in certain vertebrate and mosquito cell lines and found pathogenic to laboratory animals. One natural infection and five laboratory-acquired infections in men were also reported. GANV is antigenically related to Nairobi sheep disease virus (NSDV) of Africa, which is highly pathogenic for sheep and goats causing 70-90 per cent mortality among the susceptible population. Recent molecular studies have demonstrated that GANV is an Asian variant of NSDV and both these viruses are related to the dreaded Crimean Congo haemorrhagic fever (CCHF) group viruses. The versatility of the virus to replicate in different arthropod species, its ability to infect sheep, goat and man makes it an important zoonotic agent. |
Number of References: | 26 |
تواريخ الأحداث: | Date Created: 20100122 Date Completed: 20100402 Latest Revision: 20130418 |
رمز التحديث: | 20221213 |
PMID: | 20090098 |
قاعدة البيانات: | MEDLINE |
تدمد: | 0971-5916 |
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