دورية أكاديمية

[Expression of early developmental genes in vole Microtus rossiaemeridionalis].

التفاصيل البيبلوغرافية
العنوان: [Expression of early developmental genes in vole Microtus rossiaemeridionalis].
المؤلفون: Sorokin MA, Medvedev SP, Shevchenko AI, Slyn'ko NM, Zakiian SM
المصدر: Genetika [Genetika] 2010 Feb; Vol. 46 (2), pp. 282-6.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: Russian
بيانات الدورية: Publisher: Izdatelstvo Nauka Country of Publication: Russia (Federation) NLM ID: 0047354 Publication Model: Print Cited Medium: Print ISSN: 0016-6758 (Print) Linking ISSN: 00166758 NLM ISO Abbreviation: Genetika Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Moskva : Izdatelstvo Nauka
مواضيع طبية MeSH: Arvicolinae/*embryology , Endoderm/*metabolism , Gene Expression Regulation, Developmental/*physiology, Animals ; Arvicolinae/genetics ; Cell Line ; Female ; Genetic Markers/physiology ; Humans ; Kruppel-Like Factor 4 ; Male ; Mice ; Species Specificity
مستخلص: The expression of genes Sox2, Klf4, Myc, Sall4, Gata6, Foxa2, Hnf4a, Cdx2, Esrrb, Hand1 in cultivated cells, embryos and organs of adult voles Microtus rossiaemeridionalis was studied. High resemblance of the expression patterns of these genes in the organs of adult voles, mice and humans was demonstrated. It was established that genes Gata6, Foxa2 and Hnf4a were specifically expressed in vole extraembryonic endoderm cells, while Cdx2 and Handl genes, in trophoblast stem cells. This shows that these genes can be used markers for corresponding vole cell lines. Indirect confirmation pointing to the fact that Oct4 gene is a marker gene for epiblast cells both in the vole and mouse was obtained.
المشرفين على المادة: 0 (Genetic Markers)
0 (KLF4 protein, human)
0 (Klf4 protein, mouse)
0 (Kruppel-Like Factor 4)
تواريخ الأحداث: Date Created: 20100320 Date Completed: 20100427 Latest Revision: 20211203
رمز التحديث: 20240628
PMID: 20297663
قاعدة البيانات: MEDLINE