دورية أكاديمية
أعرض في EDS

Diagnostic and prognostic utility of electrocardiography for left ventricular hypertrophy defined by magnetic resonance imaging in relationship to ethnicity: the Multi-Ethnic Study of Atherosclerosis (MESA).

التفاصيل البيبلوغرافية
العنوان: Diagnostic and prognostic utility of electrocardiography for left ventricular hypertrophy defined by magnetic resonance imaging in relationship to ethnicity: the Multi-Ethnic Study of Atherosclerosis (MESA).
المؤلفون: Jain A; Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Tandri H, Dalal D, Chahal H, Soliman EZ, Prineas RJ, Folsom AR, Lima JA, Bluemke DA
المصدر: American heart journal [Am Heart J] 2010 Apr; Vol. 159 (4), pp. 652-8.
نوع المنشور: Comparative Study; Journal Article
اللغة: English
بيانات الدورية: Publisher: Mosby Country of Publication: United States NLM ID: 0370465 Publication Model: Print Cited Medium: Internet ISSN: 1097-6744 (Electronic) Linking ISSN: 00028703 NLM ISO Abbreviation: Am Heart J Subsets: MEDLINE
أسماء مطبوعة: Original Publication: St. Louis, MO : Mosby
مواضيع طبية MeSH: Hypertrophy, Left Ventricular/*diagnosis , Hypertrophy, Left Ventricular/*ethnology, Aged ; Electrocardiography ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Prognosis ; Sensitivity and Specificity
مستخلص: Background: Left ventricular mass is a strong predictor of cardiovascular disease (CVD), and magnetic resonance imaging (MRI) of the heart is a standard of reference for left ventricular mass measurement. Ethnicity is believed to affect electrocardiographic (ECG) performance. We evaluated the diagnostic and prognostic performance of ECG for left ventricular hypertrophy (LVH) as defined by MRI in relationship to ethnicity.
Methods: Data were analyzed from 4,967 participants (48% men, mean age 62 +/- 10 years; 39% white, 13% Chinese, 26% African American, 22% Hispanic) enrolled in the Multi-Ethic Study of Atherosclerosis (MESA) who were followed for a median of 4.8 years for incident CVD.
Results: Thirteen traditional ECG-LVH criteria were assessed, and showed overall and ethnicity-specific low sensitivity (10%-26%) and high specificity (88%-99%) in diagnosing MRI-defined LVH. Ten of 13 ECG-LVH criteria showed superior sensitivity and diagnostic performance in African Americans as compared with whites (P = .02-.001). The sum of amplitudes of S wave in V(1), S wave in V(2), and R wave in V(5) (a MESA-specific ECG-LVH criterion) offered higher sensitivity (40.4%) compared with prior ECG-LVH criteria while maintaining good specificity (90%) and diagnostic performance (receiver operating characteristic area = 0.65). In fully adjusted models, only the MESA-specific ECG-LVH criterion, Romhilt-Estes score, Framingham score, Cornell voltage, Cornell duration product, and Framingham-adjusted Cornell voltage predicted increased CVD risk (P < .05).
Conclusions: Electrocardiography has low sensitivity but high specificity for detecting MRI-defined LVH. The performance of ECG for LVH detection varies by ethnicity, with African Americans showing higher sensitivity and overall performance compared with other ethnic groups.
(Copyright 2010 Mosby, Inc. All rights reserved.)
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معلومات مُعتمدة: ZIA CL090019-01 United States ImNIH Intramural NIH HHS; N01 HC095167 United States HC NHLBI NIH HHS; N01 HC095161 United States HC NHLBI NIH HHS; N01 HC095164 United States HC NHLBI NIH HHS; ZIA EB000072-01 United States ImNIH Intramural NIH HHS; N01 HC095169 United States HC NHLBI NIH HHS; N01 HC095168 United States HC NHLBI NIH HHS; N01 HC095163 United States HC NHLBI NIH HHS; N01 HC095162 United States HC NHLBI NIH HHS; N01 HC095159 United States HC NHLBI NIH HHS; N01 HC095166 United States HC NHLBI NIH HHS; N01 HC095160 United States HC NHLBI NIH HHS; Z99 CL999999 United States ImNIH Intramural NIH HHS; N01 HC095165 United States HC NHLBI NIH HHS
تواريخ الأحداث: Date Created: 20100406 Date Completed: 20100513 Latest Revision: 20211020
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC2856691
DOI: 10.1016/j.ahj.2009.12.035
PMID: 20362725
قاعدة البيانات: MEDLINE
الوصف
تدمد:1097-6744
DOI:10.1016/j.ahj.2009.12.035