دورية أكاديمية
A third window of the posterior semicircular canal: an animal model.
| العنوان: | A third window of the posterior semicircular canal: an animal model. |
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| المؤلفون: | Nageris BI; Department of Otorhinolaryngology-Head and Neck Surgery, Rabin Medical Center, Petach Tikva, Israel., Attias J, Shemesh R, Hadar T, Preis M |
| المصدر: | The Laryngoscope [Laryngoscope] 2010 May; Vol. 120 (5), pp. 1034-7. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 8607378 Publication Model: Print Cited Medium: Internet ISSN: 1531-4995 (Electronic) Linking ISSN: 0023852X NLM ISO Abbreviation: Laryngoscope Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2009- >: Philadelphia, PA : Wiley-Blackwell Original Publication: St. Louis, Mo. : [s.n., 1896- |
| مواضيع طبية MeSH: | Fenestration, Labyrinth*, Hearing Loss, Conductive/*pathology , Semicircular Canals/*pathology , Semicircular Canals/*physiopathology , Vestibular Diseases/*pathology , Vestibular Diseases/*physiopathology , Vestibule, Labyrinth/*pathology , Vestibule, Labyrinth/*physiopathology, Animals ; Auditory Threshold/physiology ; Bone Conduction/physiology ; Brain Stem/physiopathology ; Evoked Potentials, Auditory, Brain Stem/physiology ; Gerbillinae ; Hearing Loss, Conductive/physiopathology |
| مستخلص: | Objectives/hypothesis: A third window in the vestibular apparatus has been investigated in both animals and humans, specifically in superior semicircular canal dehiscence. There are as yet no animal model studies of the effect of a third vestibular window of the posterior semicircular canal. Study Design: Original basic research study. Methods: A fenestration was drilled in the bony labyrinth over the posterior semicircular canal, preserving the membranous labyrinth, in seven healthy, 6-month-old, fat sand rats (total 10 ears). Auditory brain stem responses to low- and high-frequency acoustic stimuli delivered by air conduction and bone conduction were recorded before and after fenestration. Results: On the preoperative auditory brainstem recordings, air-conduction thresholds to clicks and tone bursts averaged, respectively, 6.5 dB and 7.5 dB, and bone-conduction thresholds, 8 dB and 4.5 dB. Postoperatively, air-conduction thresholds averaged 14.5 dB, and bone-conduction thresholds 10.5 dB and 5 dB. The change in air-conduction thresholds was statistically significant (P < .01), whereas the bone conduction thresholds remained unchanged. Conclusions: A vestibular third window in the posterior semicircular canal decreases the sensitivity to air-conducted sound stimuli, raising the air-conduction threshold. There is no change in the bone-conduction threshold. These findings agree with the theoretical model and clinical findings. |
| تواريخ الأحداث: | Date Created: 20100428 Date Completed: 20100517 Latest Revision: 20100427 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1002/lary.20831 |
| PMID: | 20422700 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1531-4995 |
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| DOI: | 10.1002/lary.20831 |