دورية أكاديمية
The performance of the Alcohol Use Disorder Identification Test (AUDIT) in detecting alcohol abuse and dependence in a population of depressed or anxious persons.
| العنوان: | The performance of the Alcohol Use Disorder Identification Test (AUDIT) in detecting alcohol abuse and dependence in a population of depressed or anxious persons. |
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| المؤلفون: | Boschloo L; Department of Psychiatry and EMGO+ Institute for Health and Care Research, VU University Medical Center, AJ Ernststraat 887, 1081 HL Amsterdam, The Netherlands. l.boschloo@vumc.nl, Vogelzangs N, Smit JH, van den Brink W, Veltman DJ, Beekman AT, Penninx BW |
| المصدر: | Journal of affective disorders [J Affect Disord] 2010 Nov; Vol. 126 (3), pp. 441-6. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7906073 Publication Model: Print Cited Medium: Internet ISSN: 1573-2517 (Electronic) Linking ISSN: 01650327 NLM ISO Abbreviation: J Affect Disord Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Amsterdam, Elsevier/North-Holland Biomedical Press. |
| مواضيع طبية MeSH: | Surveys and Questionnaires*, Alcoholism/*diagnosis , Alcoholism/*epidemiology , Anxiety Disorders/*diagnosis , Anxiety Disorders/*epidemiology , Depressive Disorder/*diagnosis , Depressive Disorder/*epidemiology, Adult ; Alcoholism/psychology ; Anxiety Disorders/psychology ; Comorbidity ; Cross-Sectional Studies ; Depressive Disorder/psychology ; Diagnosis, Dual (Psychiatry) ; Female ; Humans ; Male ; Mass Screening/statistics & numerical data ; Middle Aged ; Psychometrics/statistics & numerical data ; Reproducibility of Results |
| مستخلص: | Background: Alcohol use disorders are highly prevalent but often remain unrecognized among depressed and/or anxious persons. This study examines the performance of the Alcohol Use Disorder Identification Test (AUDIT) in detecting alcohol abuse and dependence in this high-risk group and compares it to that in healthy controls. Methods: Data from the Netherlands Study of Depression and Anxiety (NESDA) were used, including 1756 persons with a past-year depressive and/or anxiety disorder and 648 persons without a lifetime depressive and anxiety disorder. The performance of the AUDIT was compared against the gold standard of a CIDI-based diagnosis of past-year alcohol abuse or dependence by means of sensitivity, specificity and areas under receiver operating characteristic curves (AUCs). Results: The AUDIT accurately detected alcohol dependence in depressed and/or anxious men (AUC=0.89) and women (AUC==0.88), with detected cut-off points of ≥9 and ≥6, respectively, comparable to that in healthy controls (men: AUC=0.89; women: AUC=0.94). However, the overall accuracy in detecting alcohol abuse was limited in depressed/anxious men (AUC=0.74) and women (AUC=0.78) and no adequate cut-off points with both acceptable sensitivity and specificity could be identified. Limitations: Persons with a primary diagnosis of an addiction disorder were excluded and therefore the sample may not be fully representative of the most severely addicted patients. Conclusions: These findings confirm the accuracy of the AUDIT in detecting alcohol dependence, but not alcohol abuse, in depressed and/or anxious persons. Screening for alcohol dependence in this high-risk group could improve identification of persons suffering from this impairing comorbid condition. (Copyright © 2010 Elsevier B.V. All rights reserved.) |
| تواريخ الأحداث: | Date Created: 20100612 Date Completed: 20110126 Latest Revision: 20151119 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/j.jad.2010.04.019 |
| PMID: | 20537398 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1573-2517 |
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| DOI: | 10.1016/j.jad.2010.04.019 |