دورية أكاديمية
[Protontherapy: basis, indications and new technologies].
| العنوان: | [Protontherapy: basis, indications and new technologies]. |
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| عنوان ترانسليتريتد: | La protonthérapie : bases, indications et nouvelles technologies. |
| المؤلفون: | Mazal A; Institut Curie, Paris, France. alejandro.mazal@curie.net, Habrand JL, Delacroix S, Datchary J, Dendale R, Desjardins L, Ferrand R, Malka V, Fourquet A |
| المصدر: | Bulletin du cancer [Bull Cancer] 2010 Jul; Vol. 97 (7), pp. 831-46. |
| نوع المنشور: | Journal Article |
| اللغة: | French |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: France NLM ID: 0072416 Publication Model: Print Cited Medium: Internet ISSN: 1769-6917 (Electronic) Linking ISSN: 00074551 NLM ISO Abbreviation: Bull Cancer Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Jan. 2015- : Paris : Elsevier Original Publication: Paris : Masson |
| مواضيع طبية MeSH: | Proton Therapy*, Neoplasms/*radiotherapy, Adult ; Carcinoma, Non-Small-Cell Lung/radiotherapy ; Child ; Energy Transfer ; Eye Neoplasms/radiotherapy ; Humans ; Lung Neoplasms/radiotherapy ; Particle Accelerators/economics ; Particle Accelerators/instrumentation ; Photons/therapeutic use ; Radiation Oncology/methods ; Sarcoma/radiotherapy ; Skull Base Neoplasms/radiotherapy ; Spinal Neoplasms/radiotherapy ; Technology, Radiologic/instrumentation ; Technology, Radiologic/methods |
| مستخلص: | With over 70,000 patients treated worldwide, protontherapy has an evolution on their clinical applications and technological developments. The ballistic advantage of the Bragg peak gives the possibility of getting a high conformation of the dose distribution to the target volume. Protontherapy has accumulated a considerable experience in the management of selected rare malignancies such as uveal melanomas and base of the skull chordomas and chondrosarcomas. The growing interest for exploring new and more common conditions, such as prostate, lung, liver, ENT, breast carcinomas, as well as the implementation of large pediatric programs advocated by many experts has been challenged up to now by the limited access to operational proton facilities, and by the relatively slow pace of technical developments in terms of ion production, beam shaping and modelling, on-line verification etc. One challenge today is to deliver dynamic techniques with intensity modulation in clinical facilities as a standard treatment. We concentrate in this paper on the evolution of clinical indications as well as the potentialities of new technological concepts on ion production, such as dielectric walls and laser-plasma interactions. While these concepts could sooner or later translate into prototypes of highly compact equipments that would make easier the implantation of cost-effective hospital-based facilities, the feasibility of their clinical use must still be proved. |
| المشرفين على المادة: | 0 (Protons) |
| تواريخ الأحداث: | Date Created: 20100707 Date Completed: 20100817 Latest Revision: 20181201 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1684/bdc.2010.1149 |
| PMID: | 20603240 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1769-6917 |
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| DOI: | 10.1684/bdc.2010.1149 |