دورية أكاديمية
Granulocyte serology: current concepts and clinical signifcance.
| العنوان: | Granulocyte serology: current concepts and clinical signifcance. |
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| المؤلفون: | Clay ME; University of Minnesota Medical School, Department of Laboratory Medicine and Pathology, Minneapolis, MN 55455, USA., Schuller RM, Bachowski GJ |
| المصدر: | Immunohematology [Immunohematology] 2010; Vol. 26 (1), pp. 11-21. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Red Cross Country of Publication: United States NLM ID: 8806387 Publication Model: Print Cited Medium: Print ISSN: 0894-203X (Print) Linking ISSN: 0894203X NLM ISO Abbreviation: Immunohematology Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: [Washington, D.C.] : American Red Cross, [1984- |
| مواضيع طبية MeSH: | Granulocytes/*immunology , Isoantibodies/*immunology , Isoantigens/*immunology , Neutropenia/*immunology, Antibodies, Monoclonal/immunology ; Congresses as Topic ; Forecasting ; Genotype ; Histocompatibility Testing ; Humans ; Immunity, Maternally-Acquired ; Infant, Newborn ; Isoantibodies/blood ; Isoantigens/blood ; Isoantigens/classification ; Isoantigens/genetics ; Neutropenia/chemically induced ; Neutropenia/congenital ; Neutropenia/etiology ; Serologic Tests ; Serology/organization & administration ; Terminology as Topic ; Transfusion Reaction |
| مستخلص: | Applying serologic procedures to the detection of RBC and lymphocyte antigens has facilitated the identification of granulocyte antigens with established clinical significance, which are now classified in the human neutrophil antigen system. Granulocyte alloantibodies and autoantibodies have been implicated in a variety of clinical conditions including alloimmune neutropenia, autoimmune neutropenia, febrile and severe pulmonary transfusion reactions, drug-induced neutropenia, refractoriness to granulocyte transfusions, and immune neutropenia after hematopoietic stem cell transplantation. Although the intrinsically fragile nature of granulocytes contributes to the inherent challenges of granulocyte serology, several advances in laboratory procedures have improved detection of granulocyte antibodies. This review will provide a current perspective about the importance and use of granulocyte serology for detection of granulocyte antibodies that have significant medical effects. |
| Number of References: | 101 |
| المشرفين على المادة: | 0 (Antibodies, Monoclonal) 0 (Isoantibodies) 0 (Isoantigens) |
| تواريخ الأحداث: | Date Created: 20100828 Date Completed: 20101005 Latest Revision: 20171116 |
| رمز التحديث: | 20221213 |
| PMID: | 20795313 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0894-203X |
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