التفاصيل البيبلوغرافية
| العنوان: |
Increased micronucleus frequency in exfoliated cells of the buccal mucosa in hairdressers. |
| المؤلفون: |
Rickes LN; Laboratório de Genética, Centro de Ciências da Vida e da Saúde, Universidade Católica de Pelotas, Pelotas, RS, Brasil. leticiarickes@hotmail.com, Alvarengo MC, Souza TM, Garcias GL, Martino-Roth MG |
| المصدر: |
Genetics and molecular research : GMR [Genet Mol Res] 2010 Sep 28; Vol. 9 (3), pp. 1921-8. Date of Electronic Publication: 2010 Sep 28. |
| نوع المنشور: |
Journal Article |
| اللغة: |
English |
| بيانات الدورية: |
Publisher: FUNPEC Country of Publication: Brazil NLM ID: 101169387 Publication Model: Electronic Cited Medium: Internet ISSN: 1676-5680 (Electronic) Linking ISSN: 16765680 NLM ISO Abbreviation: Genet Mol Res Subsets: MEDLINE |
| أسماء مطبوعة: |
Original Publication: [Ribeirao Preto, SP Brazil] : FUNPEC, 2002- |
| مواضيع طبية MeSH: |
Air Pollutants, Occupational/*toxicity , Mouth Mucosa/*drug effects , Mouth Mucosa/*metabolism , Occupational Exposure/*adverse effects, Adolescent ; Adult ; Aged ; Brazil ; Case-Control Studies ; Female ; Humans ; Male ; Micronucleus Tests ; Middle Aged ; Sex Factors ; Young Adult |
| مستخلص: |
Hairdressers are exposed daily to chemical substances, such as dyes, chemical straighteners and curling chemicals, which can be absorbed, inhaled or possibly ingested. We analyzed the frequency of micronuclei (MNC) in exfoliated cells of the buccal mucosa of 50 hairdressers and 50 controls in Pelotas, RS, Brazil. An assessment was carried out on the incidence of MNC, binucleated cells (BNC), broken egg cells (BEC), budding cells (BC), and the sum of anomalies (SA), in 2000 cells per individual. The data were analyzed with SPSS, using the Mann-Whitney U-test, α = 0.05. The mean number of anomalies in hairdressers was 2.02 ± 3.60 MNC; 8.50 ± 5.07 BNC; 9.06 ± 3.83 BEC; 0.32 ± 0.62 BC, and 19.90 ± 9.61 SA; in controls it was 0.36 ± 1.06 MNC; 5.20 ± 4.73 BNC; 5.92 ± 2.67 BEC; 0.10 ± 0.36 BC, and 11.58 ± 6.67 SA; the differences for all parameters were significant. The non-occupational factors did not significantly influence the alterations. A significant increase of BEC (P = 0.003) was observed in the hairdressers and SA (P = 0.033) in females. The lowest income level influenced MNC (P = 0.044), and the habit of not smoking influenced SA (P = 0.020). We concluded that exposure to substances used by hairdressers is genotoxic for men. |
| المشرفين على المادة: |
0 (Air Pollutants, Occupational) |
| تواريخ الأحداث: |
Date Created: 20101001 Date Completed: 20101123 Latest Revision: 20100930 |
| رمز التحديث: |
20221213 |
| DOI: |
10.4238/vol9-3gmr941 |
| PMID: |
20882488 |
| قاعدة البيانات: |
MEDLINE |
