دورية أكاديمية
Ethnobotanical, phytochemical and toxicological studies of Xanthium strumarium L.
| العنوان: | Ethnobotanical, phytochemical and toxicological studies of Xanthium strumarium L. |
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| المؤلفون: | Islam MR; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh., Uddin MZ, Rahman MS, Tutul E, Rahman MZ, Hassan MA, Faiz MA, Hossain M, Hussain M, Rashid MA |
| المصدر: | Bangladesh Medical Research Council bulletin [Bangladesh Med Res Counc Bull] 2009 Dec; Vol. 35 (3), pp. 84-90. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Bangladesh Medical Research Council Country of Publication: Bangladesh NLM ID: 7607686 Publication Model: Print Cited Medium: Print ISSN: 0377-9238 (Print) Linking ISSN: 03779238 NLM ISO Abbreviation: Bangladesh Med Res Counc Bull Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Dacca : Bangladesh Medical Research Council Original Publication: Dacca, Bangladesh Medical Research Council. |
| مواضيع طبية MeSH: | Plant Extracts/*chemistry , Plant Extracts/*toxicity , Xanthium/*chemistry, Animals ; Bangladesh ; Ethnobotany ; Female ; Male ; Rats ; Rats, Long-Evans |
| مستخلص: | The present study describes the ethnobotanical, phytochemical, and toxicological evaluations of Xanthium strumarium L. growing in Bangladesh. In toxicity evaluation on rats, the methanol extract of seedlings showed mortality, while both seedling and mature plant extracts raised the serum alanine transaminase and aspartate transaminase values and produced significant abnormalities in the histopathology of liver and kidney of rats. On the other hand, the aqueous soluble fraction of methanol extract of mature plant (LC50 = 0.352 microg/mL) and methanol crude extract of seedlings (LC50 = 0.656 microg/mL) demonstrated significant toxicity in the brine shrimp lethality bioassay. A total of four compounds were purified and characterized as stigmasterol (1), 11-hydroxy-11-carboxy-4-oxo-1(5),2(Z)-xanthadien-12,8-olide (2), daucosterol (3) and lasidiol-10-anisate (4). The present study suggests that X. strumarium is toxic to animal. |
| المشرفين على المادة: | 0 (Plant Extracts) |
| تواريخ الأحداث: | Date Created: 20101007 Date Completed: 20101104 Latest Revision: 20191111 |
| رمز التحديث: | 20221213 |
| DOI: | 10.3329/bmrcb.v35i3.3658 |
| PMID: | 20922910 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0377-9238 |
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| DOI: | 10.3329/bmrcb.v35i3.3658 |