دورية أكاديمية
Dexamethasone - Cyclophosphamide pulse (DCP) therapy in Pemphigus.
| العنوان: | Dexamethasone - Cyclophosphamide pulse (DCP) therapy in Pemphigus. |
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| المؤلفون: | Roy R; Department of Skin, VD and Leprosy Dr. S N Medical College, Jodhpur, Rajasthan, India., Kalla G |
| المصدر: | Indian journal of dermatology, venereology and leprology [Indian J Dermatol Venereol Leprol] 1997 Nov-Dec; Vol. 63 (6), pp. 354-6. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Scientific Scholar on behalf of Indian Association of Dermatologists, Venereologists & Leprologists Country of Publication: United States NLM ID: 7701852 Publication Model: Print Cited Medium: Print ISSN: 0378-6323 (Print) Linking ISSN: 03786323 NLM ISO Abbreviation: Indian J Dermatol Venereol Leprol Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Publication: 2021- : Pittsford, NY : Scientific Scholar on behalf of Indian Association of Dermatologists, Venereologists & Leprologists Original Publication: Vellore, Indian Assn. of Dermatologists, Venereologists and Leprologists. |
| مستخلص: | Of the 37 patients enrolled for this treatment, 13 have been lost to follow up and 4 have died. Of the remaining 20, 8 are already in remission (40%), while 12 are still having active disease. Of the 8 patients who are now in remission, 1 is in phase II and taking monthly dexamethasone cyclophosphamide pulse and 50 mg cyclophosphamide daily while in 3 patients all the treatment has already been withdrawn (phase IV). All these patients are being followed up for any recurrence. The duration of remission has been more than 6 months in 7 patients (maximum 2 years). The chief side-effect observed was increased susceptibility to pyogenic and candidal infections of the skin and oral mucosa respectively. The other side-effects noted were generalized weakness and lethargy following DCP (1), irregular menstrual periods (1), amenorrhoea (1), general darkening of complexion (1), steroid psychosis (1), transient eosinophilia (1) and marked transient oligospermia. |
| تواريخ الأحداث: | Date Created: 20101015 Date Completed: 20121002 Latest Revision: 20101014 |
| رمز التحديث: | 20221213 |
| PMID: | 20944377 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0378-6323 |
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