دورية أكاديمية
Wait list death and survival benefit of kidney transplantation among nonrenal transplant recipients.
| العنوان: | Wait list death and survival benefit of kidney transplantation among nonrenal transplant recipients. |
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| المؤلفون: | Cassuto JR; Department of Surgery, Division of Transplantation, University of Pennsylvania, Philadelphia, PA, USA., Reese PP, Sonnad S, Bloom RD, Levine MH, Olthoff KM, Shaked A, Naji A, Abt P |
| المصدر: | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons [Am J Transplant] 2010 Nov; Vol. 10 (11), pp. 2502-11. |
| نوع المنشور: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 100968638 Publication Model: Print Cited Medium: Internet ISSN: 1600-6143 (Electronic) Linking ISSN: 16006135 NLM ISO Abbreviation: Am J Transplant Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2023- : [New York] : Elsevier Original Publication: Copenhagen : Munksgaard International Publishers, 2001- |
| مواضيع طبية MeSH: | Kidney Transplantation/*mortality , Waiting Lists/*mortality, Adult ; Cohort Studies ; Female ; Heart Transplantation/mortality ; Humans ; Kidney Transplantation/ethics ; Liver Transplantation/mortality ; Living Donors/statistics & numerical data ; Lung Transplantation/mortality ; Male ; Middle Aged ; Proportional Hazards Models ; Registries ; Reoperation/ethics ; Reoperation/mortality ; Retrospective Studies ; Tissue Donors/statistics & numerical data |
| مستخلص: | The disparity between the number of patients waiting for kidney transplantation and the limited supply of kidney allografts has renewed interest in the benefit from kidney transplantation experienced by different groups. This study evaluated kidney transplant survival benefit in prior nonrenal transplant recipients (kidney after liver, KALi; lung, KALu; heart, KAH) compared to primary isolated (KA1) or repeat isolated kidney (KA2) transplant. Multivariable Cox regression models were fit using UNOS data for patients wait listed and transplanted from 1995 to 2008. Compared to KA1, the risk of death on the wait list was lower for KA2 (p < 0.001;HR = 0.84;CI = 0.81-0.88), but substantially higher for KALu (p < 0.001; HR = 3.80;CI = 3.08-4.69), KAH (p < 0.001; HR = 1.92; CI = 1.66-2.22), and KALi (p < 0.001; HR = 2.69; CI = 2.46-2.95). Following kidney transplant, patient survival was greatest for KA1, similar among KA2, KALi, KAH, and inferior for KALu. Compared to the entire wait list, renal transplantation was associated with a survival benefit among all groups except KALu (p = 0.017; HR = 1.61; CI = 1.09-2.38), where posttransplant survival was inferior to the wait list population. Recipients of KA1 kidney transplantation have the greatest posttransplant survival and compared to the overall kidney wait list, the greatest survival benefit. (©2010 The Authors Journal compilation©2010 The American Society of Transplantation and the American Society of Transplant Surgeons.) |
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| معلومات مُعتمدة: | K23 DK078688 United States DK NIDDK NIH HHS; K23 DK078688-01 United States DK NIDDK NIH HHS |
| تواريخ الأحداث: | Date Created: 20101028 Date Completed: 20110209 Latest Revision: 20230124 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC2966021 |
| DOI: | 10.1111/j.1600-6143.2010.03292.x |
| PMID: | 20977641 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1600-6143 |
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| DOI: | 10.1111/j.1600-6143.2010.03292.x |