دورية أكاديمية
Neuroprotective properties of afobazole in repeated hemorrhagic stroke modeling in aged rats.
| العنوان: | Neuroprotective properties of afobazole in repeated hemorrhagic stroke modeling in aged rats. |
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| المؤلفون: | Kraineva VA; V. V. Zakusov Institute of Pharmacology, Russian Academy of Medical Sciences, Russia. niipharm@mail.ru, Seredenin SB |
| المصدر: | Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2010 Aug; Vol. 149 (2), pp. 204-7. |
| نوع المنشور: | Journal Article |
| اللغة: | English; Russian |
| بيانات الدورية: | Publisher: Springer Country of Publication: United States NLM ID: 0372557 Publication Model: Print Cited Medium: Internet ISSN: 1573-8221 (Electronic) Linking ISSN: 00074888 NLM ISO Abbreviation: Bull Exp Biol Med Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: New York : Springer Original Publication: New York, Consultants Bureau. |
| مواضيع طبية MeSH: | Ataxia/*drug therapy , Benzimidazoles/*pharmacology , Cerebral Hemorrhage, Traumatic/*drug therapy , Learning/*drug effects , Memory/*drug effects , Morpholines/*pharmacology , Neuroprotective Agents/*pharmacology, Age Factors ; Animals ; Ataxia/etiology ; Benzimidazoles/administration & dosage ; Benzimidazoles/therapeutic use ; Cerebral Hemorrhage, Traumatic/complications ; Cerebral Hemorrhage, Traumatic/mortality ; Injections, Intraperitoneal ; Male ; Morpholines/administration & dosage ; Morpholines/therapeutic use ; Neuroprotective Agents/administration & dosage ; Neuroprotective Agents/therapeutic use ; Rats |
| مستخلص: | Intraperitoneal administration of afobazole in a dose of 0.1 mg/kg over 2 weeks after repeated modeling of intracerebral post-traumatic hematoma reduces animal mortality, decreases motor coordination disturbances, and improves learning and memory processes in rats. |
| المشرفين على المادة: | 0 (2-((2-morpholino)ethylthio)-5-ethoxybenzimidazole) 0 (Benzimidazoles) 0 (Morpholines) 0 (Neuroprotective Agents) |
| تواريخ الأحداث: | Date Created: 20101130 Date Completed: 20110302 Latest Revision: 20190813 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1007/s10517-010-0908-1 |
| PMID: | 21113492 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1573-8221 |
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| DOI: | 10.1007/s10517-010-0908-1 |