دورية أكاديمية
أعرض في EDS

The effect of age on transmission of 2009 pandemic influenza A (H1N1) in a camp and associated households.

التفاصيل البيبلوغرافية
العنوان: The effect of age on transmission of 2009 pandemic influenza A (H1N1) in a camp and associated households.
المؤلفون: Sugimoto JD; Center for Statistics and Quantitative Infectious Disease, Vaccine and Infectious Disease Institute, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Borse NN, Ta ML, Stockman LJ, Fischer GE, Yang Y, Halloran ME, Longini IM Jr, Duchin JS
المصدر: Epidemiology (Cambridge, Mass.) [Epidemiology] 2011 Mar; Vol. 22 (2), pp. 180-7.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural
اللغة: English
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9009644 Publication Model: Print Cited Medium: Internet ISSN: 1531-5487 (Electronic) Linking ISSN: 10443983 NLM ISO Abbreviation: Epidemiology Subsets: MEDLINE
أسماء مطبوعة: Publication: <2000>- : Hagerstown, MD : Lippincott Williams & Wilkins
Original Publication: [Cambridge, MA : Blackwell Scientific Publications ; Chestnut Hill, MA : Epidemiology Resources, c1990-
مواضيع طبية MeSH: Camping* , Housing* , Pandemics*, Influenza A Virus, H1N1 Subtype/*isolation & purification , Influenza, Human/*epidemiology , Influenza, Human/*transmission, Adolescent ; Adult ; Age Factors ; Female ; Health Surveys ; Humans ; Male ; Models, Statistical ; Retrospective Studies ; Washington/epidemiology ; Young Adult
مستخلص: Background: A major portion of influenza disease burden during the 2009 pandemic was observed among young people.
Methods: We examined the effect of age on the transmission of influenza-like illness associated with the 2009 pandemic influenza A (H1N1) virus (pH1N1) for an April-May 2009 outbreak among youth-camp participants and household contacts in Washington State.
Results: An influenza-like illness attack rate of 51% was found among 96 camp participants. We observed a cabin secondary attack rate of 42% (95% confidence interval = 21%-66%) and a camp local reproductive number of 2.7 (1.7-4.1) for influenza-like illness among children (less than 18 years old). Among the 136 contacts in the 41 households with an influenza-like illness index case who attended the camp, the influenza-like illness secondary attack rate was 11% for children (5%-21%) and 4% for adults (2%-8%). The odds ratio for influenza-like illness among children versus adults was 3.1 (1.3-7.3).
Conclusions: The strong age effect, combined with the low number of susceptible children per household (1.2), plausibly explains the lower-than-expected household secondary attack rate for influenza-like illness, illustrating the importance of other venues where children congregate for sustaining community transmission. Quantifying the effects of age on pH1N1 transmission is important for informing effective intervention strategies.
References: MMWR Morb Mortal Wkly Rep. 2009 May 8;58(17):467-70. (PMID: 19444150)
Science. 2009 Oct 30;326(5953):729-33. (PMID: 19745114)
MMWR Morb Mortal Wkly Rep. 2009 Oct 23;58(41):1143-6. (PMID: 19847148)
Br J Gen Pract. 1990 Jan;40(330):10-2. (PMID: 2107831)
N Engl J Med. 2001 Mar 22;344(12):889-96. (PMID: 11259722)
J Infect Dis. 2010 Apr 1;201(7):984-92. (PMID: 20187740)
MMWR Morb Mortal Wkly Rep. 2009 May 1;58(16):435-7. (PMID: 19407739)
Am J Epidemiol. 1982 Aug;116(2):212-27. (PMID: 7114033)
Am J Epidemiol. 1975 Dec;102(6):553-63. (PMID: 1202957)
MMWR Morb Mortal Wkly Rep. 2009 May 8;58(17):470-2. (PMID: 19444151)
Euro Surveill. 2009 Sep 03;14(35):. (PMID: 19728982)
Science. 2009 Jun 19;324(5934):1557-61. (PMID: 19433588)
N Engl J Med. 2009 Dec 31;361(27):2619-27. (PMID: 20042753)
Commun Dis Rep CDR Rev. 1995 Nov 10;5(12):R177-9. (PMID: 8541938)
N Engl J Med. 1978 Mar 16;298(11):587-92. (PMID: 628375)
Am J Epidemiol. 1985 Jun;121(6):811-22. (PMID: 4014174)
Emerg Infect Dis. 2010 Apr;16(4):631-7. (PMID: 20350377)
Euro Surveill. 2009 Jul 09;14(27):. (PMID: 19589329)
Science. 2009 Aug 28;325(5944):1071-2; author reply 1072-3. (PMID: 19713507)
Epidemiol Infect. 2011 Jan;139(1):41-4. (PMID: 20561390)
MMWR Morb Mortal Wkly Rep. 2009 Sep 11;58(35):969-72. (PMID: 19745803)
Lancet Infect Dis. 2009 Aug;9(8):473-81. (PMID: 19628172)
N Engl J Med. 2009 Dec 31;361(27):2628-36. (PMID: 20042754)
Euro Surveill. 2009 Jul 09;14(27):. (PMID: 19589330)
J R Stat Soc Ser C Appl Stat. 2006 May;55(3):317-330. (PMID: 22457545)
MMWR Morb Mortal Wkly Rep. 2009 Apr 24;58(15):400-2. (PMID: 19390508)
معلومات مُعتمدة: R01 AI032042 United States AI NIAID NIH HHS; U01 GM070749 United States GM NIGMS NIH HHS; R01-AI32042 United States AI NIAID NIH HHS; U01-GM070749 United States GM NIGMS NIH HHS
تواريخ الأحداث: Date Created: 20110115 Date Completed: 20110613 Latest Revision: 20211020
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC3755879
DOI: 10.1097/EDE.0b013e3182060ca5
PMID: 21233714
قاعدة البيانات: MEDLINE
الوصف
تدمد:1531-5487
DOI:10.1097/EDE.0b013e3182060ca5