[Role of G(-43)A polymorphism in the promoter region of the Xist gene in non-random X-chromosome inactivation in intraspecific hybrid voles].

التفاصيل البيبلوغرافية
العنوان:	[Role of G(-43)A polymorphism in the promoter region of the Xist gene in non-random X-chromosome inactivation in intraspecific hybrid voles].
المؤلفون:	Orishchenko KE, Elisafenko EA, Zakiian SM
المصدر:	Genetika [Genetika] 2010 Oct; Vol. 46 (10), pp. 1397-400.
نوع المنشور:	Journal Article; Research Support, Non-U.S. Gov't
اللغة:	Russian
بيانات الدورية:	Publisher: Izdatelstvo Nauka Country of Publication: Russia (Federation) NLM ID: 0047354 Publication Model: Print Cited Medium: Print ISSN: 0016-6758 (Print) Linking ISSN: 00166758 NLM ISO Abbreviation: Genetika Subsets: MEDLINE
أسماء مطبوعة:	Original Publication: Moskva : Izdatelstvo Nauka
مواضيع طبية MeSH:	Polymorphism, Single Nucleotide, Chimera/genetics , Promoter Regions, Genetic/genetics , RNA, Untranslated/genetics , X Chromosome/genetics , X Chromosome Inactivation/genetics, Animals ; Arvicolinae ; CCCTC-Binding Factor ; Chimera/metabolism ; Female ; Male ; RNA, Untranslated/metabolism ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; X Chromosome/metabolism
مستخلص:	Interaction of transcription factor CTCF with the minimal promoter of Xist gene was investigated in intraspecific hybrids ofcommon voles. CTCF was shown to bind with the minimal promoter region in vivo. However, the experiments of the delay in gel resulted in the absence of interaction between the CTCF factor and its potential binding site. Probably, G(-43)A substitution influences binding efficacy of another transcription factor such as activator protein 2, AP2.
المشرفين على المادة:	0 (CCCTC-Binding Factor) 0 (RNA, Untranslated) 0 (Repressor Proteins)
تواريخ الأحداث:	Date Created: 20110125 Date Completed: 20110209 Latest Revision: 20171116
رمز التحديث:	20221213
PMID:	21254564
قاعدة البيانات:	MEDLINE

الوصف
تدمد:	0016-6758