دورية أكاديمية
[Intercalary heterochromatin in the genome of Drosophila].
| العنوان: | [Intercalary heterochromatin in the genome of Drosophila]. |
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| المؤلفون: | Zhimulev IF, Beliaeva ES, Andreeva EN, Andreenkova NG, Babenko VN, Beliakin SN, Boldyreva LV, Brusentsova IV, Demakov SA, Zykov IA, Kokoza EB, Kolesnikova TD, Maksimov DA, Makulin IV, Pindiurin AV, Semeshin VF, Khoroshko VA |
| المصدر: | Genetika [Genetika] 2010 Oct; Vol. 46 (10), pp. 1405-8. |
| نوع المنشور: | English Abstract; Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | Russian |
| بيانات الدورية: | Publisher: Izdatelstvo Nauka Country of Publication: Russia (Federation) NLM ID: 0047354 Publication Model: Print Cited Medium: Print ISSN: 0016-6758 (Print) Linking ISSN: 00166758 NLM ISO Abbreviation: Genetika Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Moskva : Izdatelstvo Nauka |
| مواضيع طبية MeSH: | DNA/*genetics , DNA Replication/*physiology , Genome, Insect/*physiology , Polytene Chromosomes/*genetics , S Phase/*physiology, Animals ; DNA/biosynthesis ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Drosophila Proteins/genetics ; Drosophila Proteins/metabolism ; Drosophila melanogaster ; Polytene Chromosomes/metabolism |
| مستخلص: | The modern concept of intercalary heterochromatin as polytene chromosome regions exhibiting a number of specific characteristics is formulated. DNA constituting these regions is replicated late in the S period; therefore, some strands of polytene chromosomes are underrepresented; i.e., they are underreplicated. Late-replicating regions account for about 7% of the genome; genes are located there in clusters of as many as 40. In general, the gene density in the clusters is substantially lower than in the main part of the genome. Late-replicating regions have an inactivating capacity: genes incorporated into these regions as parts of transposons are inactivated with a higher probability. These regions contain a specific protein SUUR affecting the rate of replication completion. |
| المشرفين على المادة: | 0 (DNA-Binding Proteins) 0 (Drosophila Proteins) 0 (SuUR protein, Drosophila) 9007-49-2 (DNA) |
| تواريخ الأحداث: | Date Created: 20110125 Date Completed: 20110209 Latest Revision: 20121115 |
| رمز التحديث: | 20221213 |
| PMID: | 21254566 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0016-6758 |
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