دورية أكاديمية
Release of iron from ferritin by 6-hydroxydopamine under aerobic and anaerobic conditions.
العنوان: | Release of iron from ferritin by 6-hydroxydopamine under aerobic and anaerobic conditions. |
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المؤلفون: | Lode HN; Children's Hospital, Dept. Hematology and Oncology, University of Tuebingen, FRG., Bruchelt G, Rieth AG, Niethammer D |
المصدر: | Free radical research communications [Free Radic Res Commun] 1990; Vol. 11 (1-3), pp. 153-8. |
نوع المنشور: | Comparative Study; Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Harwood Academic Publishers Country of Publication: Switzerland NLM ID: 8709453 Publication Model: Print Cited Medium: Print ISSN: 8755-0199 (Print) Linking ISSN: 87550199 NLM ISO Abbreviation: Free Radic Res Commun Subsets: MEDLINE |
أسماء مطبوعة: | Publication: Yverdon-Les-Bains : Harwood Academic Publishers Original Publication: Chur ; New York : G+B/Harwood, c1985- |
مواضيع طبية MeSH: | Ferritins/*metabolism , Hydroxydopamines/*pharmacology , Iron/*metabolism, Aerobiosis ; Anaerobiosis ; Ascorbic Acid/pharmacology ; Catalase/pharmacology ; Oxidopamine ; Superoxide Dismutase/pharmacology |
مستخلص: | 6-hydroxydopamine (6-OHDA) proved to be a very effective agent for iron release from ferritin. Iron release was enhanced in the presence of SOD, catalase and under anaerobic conditions. Ascorbic acid, a well known agent able to release iron from ferritin, increased the amount of released iron in more than an additive manner when used in combination with 6-OHDA. Similar to 6-OHDA, 6-hydroxydopa (Topa) and 1,2,4-benzenetriol were also able to release iron in large amounts; in contrast, catecholamines and other benzenediols were comparatively ineffective. |
المشرفين على المادة: | 0 (Hydroxydopamines) 8HW4YBZ748 (Oxidopamine) 9007-73-2 (Ferritins) E1UOL152H7 (Iron) EC 1.11.1.6 (Catalase) EC 1.15.1.1 (Superoxide Dismutase) PQ6CK8PD0R (Ascorbic Acid) |
تواريخ الأحداث: | Date Created: 19900101 Date Completed: 19910415 Latest Revision: 20191029 |
رمز التحديث: | 20221213 |
DOI: | 10.3109/10715769009109678 |
PMID: | 2127409 |
قاعدة البيانات: | MEDLINE |
تدمد: | 8755-0199 |
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DOI: | 10.3109/10715769009109678 |