دورية أكاديمية
Management of early hepatic arterial thrombosis after pediatric living-donor liver transplantation.
| العنوان: | Management of early hepatic arterial thrombosis after pediatric living-donor liver transplantation. |
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| المؤلفون: | Sevmis S; Department of General Surgery, Başkent University Faculty of Medicine, Ankara, Turkey., Karakayali H, Tutar NU, Boyvat F, Ozcay F, Torgay A, Haberal M |
| المصدر: | Transplantation proceedings [Transplant Proc] 2011 Mar; Vol. 43 (2), pp. 605-8. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Science Inc Country of Publication: United States NLM ID: 0243532 Publication Model: Print Cited Medium: Internet ISSN: 1873-2623 (Electronic) Linking ISSN: 00411345 NLM ISO Abbreviation: Transplant Proc Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: New York, N.Y. : Elsevier Science Inc. Original Publication: New York Stratton. |
| مواضيع طبية MeSH: | Living Donors*, Hepatic Artery/*pathology , Liver/*blood supply , Liver Transplantation/*methods , Thrombosis/*therapy, Adolescent ; Child ; Child, Preschool ; Female ; Graft Rejection ; Humans ; Liver/pathology ; Male ; Pediatrics/methods ; Thrombolytic Therapy ; Ultrasonography, Doppler/methods |
| مستخلص: | Purpose: Early hepatic arterial thrombosis after living-donor liver transplantation is a cause of graft loss and patient mortality. We analyzed early hepatic arterial thrombosis after pediatric living-donor liver transplantation. Materials and Methods: Since September 2001, we performed 122 living-donor liver transplants on 119 children. Ten hepatic arterial thromboses developed in the early postoperative period. The 7 male and 4 female patients of overall mean age of 6.3±6.1 years underwent 5 left lateral segment, 3 right lobe, and 2 left lobe transplantations. Results: Among 10 children with hepatic arterial thrombosis, 8 diagnoses were made before any elevation of liver function tests. One child displayed fever at the time of the hepatic arterial thrombosis. The median time for diagnosis was 5 days. Hepatic arterial thrombosis was treated with interventional radiologic techniques in 9 children, with 1 undergoing surgical exploration owing to failed radiologic approaches, and a reanastomosis using a polytetrafluoroethylene graft. Successful revascularization was achieved in all children, except 1. Four children died, the remaining 6 are alive with good graft function. During the mean follow-up of 52.7±18.8 months, multiple intrahepatic biliary stenoses were identified in 1 child. Conclusion: Routine Doppler ultrasonography is effective for the early diagnosis of hepatic arterial thrombosis. Interventional radiologic approaches such as arterial thrombolysis and intraluminal stent placement should be the first therapeutic choices for patients with early hepatic arterial thrombosis; if radiologic methods fail, one must consider surgical exploration or retransplantation. (Copyright © 2011 Elsevier Inc. All rights reserved.) |
| تواريخ الأحداث: | Date Created: 20110329 Date Completed: 20110722 Latest Revision: 20110328 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1016/j.transproceed.2011.01.011 |
| PMID: | 21440775 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1873-2623 |
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| DOI: | 10.1016/j.transproceed.2011.01.011 |