دورية أكاديمية
The diabetic foot and leg: combined He-Ne and infrared low-intensity lasers improve skin blood perfusion and prevent potential complications. A prospective study on 30 Egyptian patients.
العنوان: | The diabetic foot and leg: combined He-Ne and infrared low-intensity lasers improve skin blood perfusion and prevent potential complications. A prospective study on 30 Egyptian patients. |
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المؤلفون: | Saied GM; Departments of Internal Medicine and General Surgery, Faculty of Medicine, Cairo University, Cairo, Egypt. gamal44@hotmail.com, Kamel RM, Labib AM, Said MT, Mohamed AZ |
المصدر: | Lasers in medical science [Lasers Med Sci] 2011 Sep; Vol. 26 (5), pp. 627-32. Date of Electronic Publication: 2011 Apr 01. |
نوع المنشور: | Journal Article; Randomized Controlled Trial |
اللغة: | English |
بيانات الدورية: | Publisher: Springer Country of Publication: England NLM ID: 8611515 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-604X (Electronic) Linking ISSN: 02688921 NLM ISO Abbreviation: Lasers Med Sci Subsets: MEDLINE |
أسماء مطبوعة: | Publication: London : Springer Original Publication: London : Baillière Tindall, c1986- |
مواضيع طبية MeSH: | Diabetic Foot/*radiotherapy , Infrared Rays/*therapeutic use , Lasers, Gas/*therapeutic use , Low-Level Light Therapy/*methods, Adult ; Diabetic Foot/physiopathology ; Egypt ; Female ; Humans ; Laser-Doppler Flowmetry ; Leg/blood supply ; Male ; Middle Aged ; Prospective Studies ; Regional Blood Flow/radiation effects ; Skin/blood supply ; Skin/radiation effects |
مستخلص: | The objective of this study was to examine skin blood flow in diabetic patients having disease-related skin lesions, and to evaluate possible improvement imposed by low-intensity laser therapy (LILT) as a new treatment modality. Thirty patients (in addition to 15 controls receiving conventional treatment = group II and 15 others receiving no treatment = group III) having diabetes-related skin lesions were tested for skin blood flow by laser Doppler flowmetry. Group I patients received LILT by a specified dosimetry. This was by combined uniform He-Ne and infrared lasers delivered by a scanner over the affected area. This study used a paired t test to determine the significance of blood flow recovery after treatment within each group while Independent t test compared results between the three groups. The level of significance was p < 0.05. The most frequently detected diabetes specific skin lesions were dryness, nail changes, hair loss, infections, itching, and frank eczema-like reactions, mostly in combinations (76%). This pattern appears specific for Egyptians as it is different from data registered in foreign literature. The minimum perfusion flow improved from 16.45 before LILT to 25.94 after, while maximum flow recovered from 32.91 to 48.47 and basal perfusion changed from 24.68 to 34.84 blood perfusion units. The percentage change in perfusion values was 23.17. All these were statistically significant. The study demonstrates that diabetes-linked skin lesions have a special pattern in Egyptians and are apparently caused by deranged skin blood flow .The deficit is measurable by laser flowmetry and can be partially reversed by LILT. |
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تواريخ الأحداث: | Date Created: 20110402 Date Completed: 20111215 Latest Revision: 20211020 |
رمز التحديث: | 20231215 |
DOI: | 10.1007/s10103-011-0911-4 |
PMID: | 21455785 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1435-604X |
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DOI: | 10.1007/s10103-011-0911-4 |