دورية أكاديمية
The efficacy of anticonvulsants on orofacial pain: a systematic review.
| العنوان: | The efficacy of anticonvulsants on orofacial pain: a systematic review. |
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| المؤلفون: | Martin WJ; Department of Oral and Maxillofacial Surgery/Oral Pathology, Vrije Universiteit Medical Center/Academic Center for Dentistry Amsterdam, Amsterdam, The Netherlands., Forouzanfar T |
| المصدر: | Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics [Oral Surg Oral Med Oral Pathol Oral Radiol Endod] 2011 May; Vol. 111 (5), pp. 627-33. |
| نوع المنشور: | Journal Article; Review; Systematic Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 9508562 Publication Model: Print Cited Medium: Internet ISSN: 1528-395X (Electronic) Linking ISSN: 10792104 NLM ISO Abbreviation: Oral Surg Oral Med Oral Pathol Oral Radiol Endod Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2004- : St. Louis, MO : Elsevier Original Publication: St. Louis, MO : Mosby-Year Book, Inc., c1995- |
| مواضيع طبية MeSH: | Anticonvulsants/*therapeutic use , Facial Pain/*drug therapy , Trigeminal Neuralgia/*drug therapy, Amines/therapeutic use ; Burning Mouth Syndrome/drug therapy ; Carbamazepine/therapeutic use ; Clonazepam/therapeutic use ; Cyclohexanecarboxylic Acids/therapeutic use ; Gabapentin ; Humans ; Lamotrigine ; Masticatory Muscles/physiopathology ; Pimozide/therapeutic use ; Randomized Controlled Trials as Topic ; Tocainide/therapeutic use ; Triazines/therapeutic use ; gamma-Aminobutyric Acid/therapeutic use |
| مستخلص: | Objective: Controversy exists about the effectiveness of anticonvulsants for the management of orofacial pain disorders. To ascertain appropriate therapies, a systematic review was conducted of existing randomized controlled trials. Study Design: Trials were identified from PubMed, Cochrane, and Ovid Medline databases from 1962 through March 2010, from references in retrieved reports, and from references in review articles. Eight useful trials were identified for this review. Six studies were randomized placebo-controlled trials and 2 studies were randomized active-controlled. Two independent investigators reviewed these articles by using a 15-item checklist. Results: Four studies were classified as "high quality." However, heterogeneity of the trials and the small sample sizes precluded the drawing of firm conclusions about the efficacy of the interventions studied on orofacial pain patients. Conclusions: There is limited to moderate evidence supporting the efficacy of commonly used anticonvulsants for treatment of patients with orofacial pain disorders. More randomized controlled trials are needed on the efficacy of anticonvulsants. (Copyright © 2011 Mosby, Inc. All rights reserved.) |
| التعليقات: | Comment in: Oral Surg Oral Med Oral Pathol Oral Radiol. 2012 Apr;113(4):429; author reply 429-30. (PMID: 22668424) |
| المشرفين على المادة: | 0 (Amines) 0 (Anticonvulsants) 0 (Cyclohexanecarboxylic Acids) 0 (Triazines) 1HIZ4DL86F (Pimozide) 27DXO59SAN (Tocainide) 33CM23913M (Carbamazepine) 56-12-2 (gamma-Aminobutyric Acid) 5PE9FDE8GB (Clonazepam) 6CW7F3G59X (Gabapentin) U3H27498KS (Lamotrigine) |
| SCR Disease Name: | Stomatodynia |
| تواريخ الأحداث: | Date Created: 20110419 Date Completed: 20110822 Latest Revision: 20181201 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.tripleo.2011.01.033 |
| PMID: | 21497736 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1528-395X |
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| DOI: | 10.1016/j.tripleo.2011.01.033 |