دورية أكاديمية
أعرض في EDS

SNOLL. Sentinel node and occult (impalpable) lesion localization in breast cancer.

التفاصيل البيبلوغرافية
العنوان: SNOLL. Sentinel node and occult (impalpable) lesion localization in breast cancer.
المؤلفون: Thind CR; Radiology Department, St Helens and Knowsley Teaching Hospitals NHS Trust, Prescott, Liverpool, UK. thindr@aol.com, Tan S, Desmond S, Harris O, Ramesh HS, Chagla L, Ray A, Audisio R
المصدر: Clinical radiology [Clin Radiol] 2011 Sep; Vol. 66 (9), pp. 833-9. Date of Electronic Publication: 2011 May 04.
نوع المنشور: Evaluation Study; Journal Article
اللغة: English
بيانات الدورية: Publisher: Blackwell Scientific Publications Ltd Country of Publication: England NLM ID: 1306016 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-229X (Electronic) Linking ISSN: 00099260 NLM ISO Abbreviation: Clin Radiol Subsets: MEDLINE
أسماء مطبوعة: Publication: Oxford : Blackwell Scientific Publications Ltd
Original Publication: Edinburgh, Livingstone.
مواضيع طبية MeSH: Breast/*diagnostic imaging , Breast Neoplasms/*diagnostic imaging , Lymph Nodes/*diagnostic imaging , Lymph Nodes/*pathology , Sentinel Lymph Node Biopsy/*methods, Adult ; Aged ; Breast/pathology ; Breast Neoplasms/pathology ; Female ; Humans ; Lymphatic Metastasis ; Middle Aged ; Prospective Studies ; Radionuclide Imaging ; Sensitivity and Specificity ; Ultrasonography, Mammary
مستخلص: Aim: To evaluate the efficacy and safety for use of dual radioisotopes for localization of occult (impalpable) breast lesions and sentinel node biopsy as a combined technique (SNOLL) using a lower dose than previous studies.
Materials and Methods: One hundred and twenty-seven SNOLL procedures were performed. The impalpable breast lesions were localized with an intra-lesion injection of 0.2 ml of (99m)Tc MAA (1 MBq) with a particle size of 10-90 μm (radio-guided occult lesion localization, or ROLL) 1 to 4 h before surgery. Sentinel node localization was performed using 0.2 mls of (99)Tc nanocolloid (20 MBq) particle size no greater than 80 nm injected subdermally in the periareolar region within the index quadrant, the night before or the morning of surgery.
Results: Lesion localization was consistently achieved with a lower dose than that described in other studies without the need to use scintigraphy or additional imaging with radioopaque contrast medium. One hundred percent lesion localization with a negative clearance margin of 94.8% and 100% sentinel node localization was achieved. The use of dual radioisotopes with the lower dose used for ROLL did not compromise the localization of the impalpable lesion or the sentinel nodes.
Conclusion: The combined use of radioisotopes for lesion and sentinel node removal is feasible and reliable with the lower radioisotope dose suggested compared with previously published studies. This method should be recommended as a standard procedure for SNOLL.
(Copyright © 2011 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.)
تواريخ الأحداث: Date Created: 20110507 Date Completed: 20111014 Latest Revision: 20191210
رمز التحديث: 20231215
DOI: 10.1016/j.crad.2011.02.017
PMID: 21546007
قاعدة البيانات: MEDLINE
الوصف
تدمد:1365-229X
DOI:10.1016/j.crad.2011.02.017