دورية أكاديمية
أعرض في EDS

Midterm clinical and angiographic follow-up for the first Food and Drug Administration-approved prospective, Single-Arm Trial of Primary Stenting for Stroke: SARIS (Stent-Assisted Recanalization for Acute Ischemic Stroke).

التفاصيل البيبلوغرافية
العنوان: Midterm clinical and angiographic follow-up for the first Food and Drug Administration-approved prospective, Single-Arm Trial of Primary Stenting for Stroke: SARIS (Stent-Assisted Recanalization for Acute Ischemic Stroke).
المؤلفون: Levy EI; Department of Neurosurgery, University at Buffalo, State University of New York, Buffalo, NY, USA. elevy@ubns.com, Rahman M, Khalessi AA, Beyer PT, Natarajan SK, Hartney ML, Fiorella DJ, Hopkins LN, Siddiqui AH, Mocco J
المصدر: Neurosurgery [Neurosurgery] 2011 Oct; Vol. 69 (4), pp. 915-20; discussion 920.
نوع المنشور: Clinical Trial; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Lippincott Williams & Wilkins, Inc Country of Publication: United States NLM ID: 7802914 Publication Model: Print Cited Medium: Internet ISSN: 1524-4040 (Electronic) Linking ISSN: 0148396X NLM ISO Abbreviation: Neurosurgery Subsets: MEDLINE
أسماء مطبوعة: Publication: 2022- : [Philadelphia] : Lippincott Williams & Wilkins, Inc.
Original Publication: Baltimore, Williams & Wilkins.
مواضيع طبية MeSH: Stents*, Angioplasty/*adverse effects , Angioplasty/*instrumentation , Postoperative Complications/*epidemiology , Stroke/*surgery, Cerebral Angiography ; Humans ; United States ; United States Food and Drug Administration
مستخلص: Background: Although early data demonstrate encouraging angiographic results following intracranial stent deployment for acute ischemic stroke, longer-term follow-up is necessary to evaluate the clinical outcomes, as well as the durability of angiographic results.
Objective: We report 6-month clinical and radiologic follow-up data of the 20 patients prospectively enrolled in the Stent-Assisted Recanalization in acute Ischemic Stroke (SARIS) trial.
Methods: Twenty patients were prospectively enrolled to receive self-expanding intra-arterial stents as first-line therapy for acute ischemic stroke treatment. Patients were scheduled for follow-up 6-months after treatment for clinical evaluation (modified Rankin Scale [mRS] score obtained by a trained certified research nurse/nurse practitioner) and repeat cerebral angiography. Angiographic interpretation was performed by an independent adjudicator.
Results: At 6 months, the mRS score was ≤3 in 60% of patients (n = 12) and was ≤2 in 55% of patients (n = 11). Mortality at the 6-month follow-up was 35% (n = 7). Follow-up angiography was performed for 85% (11 of 13) of surviving patients. All patients undergoing angiographic follow-up demonstrated Thrombolysis in Myocardial Infarction 3 flow on digital subtraction angiography or stent patency on computed tomographic angiography. None of the patients demonstrated evidence of in-stent stenosis (≥50% vessel narrowing).
Conclusion: The midterm angiographic and clinical results following intracranial stent deployment for acute ischemic stroke are encouraging. Further study of primary stent-for-stroke treatment is warranted.
التعليقات: Comment in: Neurosurgery. 2011 Dec;69(6):E1338; author reply E1338-9. (PMID: 21866070)
معلومات مُعتمدة: 1R01NS064592-01A1 United States NS NINDS NIH HHS
تواريخ الأحداث: Date Created: 20110510 Date Completed: 20111230 Latest Revision: 20110913
رمز التحديث: 20231215
DOI: 10.1227/NEU.0b013e318222afd1
PMID: 21552168
قاعدة البيانات: MEDLINE
الوصف
تدمد:1524-4040
DOI:10.1227/NEU.0b013e318222afd1