دورية أكاديمية
Squamous cell carcinoma of the tongue and floor of the mouth: analysis of survival rate and independent prognostic factors in the Amazon region.
| العنوان: | Squamous cell carcinoma of the tongue and floor of the mouth: analysis of survival rate and independent prognostic factors in the Amazon region. |
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| المؤلفون: | Pontes FS; João de Barros Barreto University Hospital, Federal University of Pará, Belém, Pará, Brazil. felipepfonseca@hotmail.com, Carneiro JT Jr, Fonseca FP, da Silva TS, Pontes HA, Pinto Ddos S Jr |
| المصدر: | The Journal of craniofacial surgery [J Craniofac Surg] 2011 May; Vol. 22 (3), pp. 925-30. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9010410 Publication Model: Print Cited Medium: Internet ISSN: 1536-3732 (Electronic) Linking ISSN: 10492275 NLM ISO Abbreviation: J Craniofac Surg |
| أسماء مطبوعة: | Publication: <2014-> : Hagerstown, MD : Lippincott Williams & Wilkins Original Publication: Burlington, Ont. : B.C. Decker, c1990- |
| مواضيع طبية MeSH: | Carcinoma, Squamous Cell/*epidemiology , Mouth Neoplasms/*epidemiology , Tongue Neoplasms/*epidemiology, Adult ; Aged ; Aged, 80 and over ; Brazil/epidemiology ; Carcinoma, Squamous Cell/diagnosis ; Carcinoma, Squamous Cell/therapy ; Female ; Humans ; Male ; Middle Aged ; Mouth Neoplasms/diagnosis ; Mouth Neoplasms/therapy ; Neoplasm Staging ; Prognosis ; Proportional Hazards Models ; Risk Factors ; Survival Rate ; Tongue Neoplasms/diagnosis ; Tongue Neoplasms/therapy ; Treatment Outcome |
| مستخلص: | Oral squamous cell carcinoma (OSCC) accounts for more than 95% of all malignant neoplasms in the oral cavity. Although several studies have shown the epidemiology of this cancer in Brazil, there do not seem to be any studies that describe the prognostic factors related to OSCC in the Amazon region. Therefore, the aim of this study was to determine the survival rate and prognostic significance of different factors in patients from this region affected by OSCC. Data from 85 patients with histologically confirmed squamous cell carcinoma of the tongue and floor of the mouth identified from the Ofir Loyola Hospital archives were collected and analyzed using univariate (log-rank test) and multivariate (Cox proportional hazard model) tests. The overall 5-year survival rate was found to be 27%. Univariate analysis showed that the 5-year survival rate was significantly higher for younger (≤ 45 y) female patients, patients with T1-2 tumors and clinically clear neck nodes (N0), patients with early stage cancers (AJCC stage I-II), and patients treated with surgical procedures. However, multivariate analysis showed that the 5-year survival rate was significantly higher only in the younger patients and those who underwent surgical treatment. The age of the patient at the moment of diagnosis and treatment with surgical procedures were the only independent prognostic factors that affected the 5-year survival rate of the patients in this region. |
| تواريخ الأحداث: | Date Created: 20110512 Date Completed: 20110929 Latest Revision: 20110519 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1097/SCS.0b013e31820fe1cb |
| PMID: | 21558919 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1536-3732 |
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| DOI: | 10.1097/SCS.0b013e31820fe1cb |