دورية أكاديمية

[Parvovirus B19 infections. The cause of fifth disease-erythema infectiosum--can also cause aplastic crises, fetal damage and polyarthritis].

التفاصيل البيبلوغرافية
العنوان: [Parvovirus B19 infections. The cause of fifth disease-erythema infectiosum--can also cause aplastic crises, fetal damage and polyarthritis].
عنوان ترانسليتريتد: Parvovirus B19 infektionen. Arsagen til den femte børnesygdom-erythema infectiosum--kan også føre til aplastiske kriser, fosterskader og polyarthritis.
المؤلفون: Hornsleth A; Københavns Universitet, Institut for Medicinsk Mikrobiologi., Carlsen KM
المصدر: Ugeskrift for laeger [Ugeskr Laeger] 1990 May 07; Vol. 152 (19), pp. 1354-7.
نوع المنشور: English Abstract; Journal Article; Review
اللغة: Danish
بيانات الدورية: Publisher: Den Alm Danske Laegerforening Country of Publication: Denmark NLM ID: 0141730 Publication Model: Print Cited Medium: Print ISSN: 0041-5782 (Print) Linking ISSN: 00415782 NLM ISO Abbreviation: Ugeskr Laeger Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Copenhagen : Den Alm Danske Laegerforening
مواضيع طبية MeSH: Anemia, Aplastic/*microbiology , Arthritis, Infectious/*microbiology , Erythema/*microbiology , Fetal Diseases/*microbiology , Parvoviridae Infections/*complications, Adolescent ; Adult ; Child ; Child, Preschool ; Female ; Humans ; Infant, Newborn ; Male ; Pregnancy ; Pregnancy Complications, Infectious/microbiology
مستخلص: Human parvovirus B19 can be an important etiological factor in aplastic crises in patients with chronic hemolytic anemia, in fetal damage, and in acute polyarthritis. B19-virus can only be grown in cell cultures established from human bone marrow, where the virus production occurs in erythroblasts. Parvovirus can cause severe, often fatal, infections in various kinds of animals, also in their fetuses, and many cases of teratogenic changes have been described. The B19-infection is diagnosed by demonstration of either IgM antibodies or B19-DNA in serum samples obtained in the early phases of infection. Patients with EI are infectious before skin eruptions occur, i.e. in the prodromal phase where virus can be detected in respiratory secretion. Transmission of the infection by concentrated, heat-treated factor preparations has been reported. Acute polyarthritis accompanying B19-infections has most often been described to affect the finger, hand and knee joints in adult women. Maternal B19-infections can be complicated by intrauterine infections damaging the fetus and resulting in abortion, hydrops fetalis or stillbirth. The B19-infection has not with certainty been found to be teratogenic. Recent studies seem to show that about 10-20% of primary maternal infections can be complicated by fetal damage, but until further this percentage should be regarded with great reservation.
Number of References: 28
تواريخ الأحداث: Date Created: 19900507 Date Completed: 19900625 Latest Revision: 20061115
رمز التحديث: 20221208
PMID: 2160748
قاعدة البيانات: MEDLINE