دورية أكاديمية

[Clinical significance of intermittent sinusoidal fetal heart rate at third trimester].

التفاصيل البيبلوغرافية
العنوان: [Clinical significance of intermittent sinusoidal fetal heart rate at third trimester].
المؤلفون: Guo XH; Department of Obstetrics and Gynecology, Second School of Clinical Medicine, Jinan University, Shenzhen 518020, China. ghgl@21cn.com, Zhang HY, Wang YL, Li HY, Liang HP
المصدر: Zhonghua fu chan ke za zhi [Zhonghua Fu Chan Ke Za Zhi] 2011 May; Vol. 46 (5), pp. 342-4.
نوع المنشور: English Abstract; Journal Article
اللغة: Chinese
بيانات الدورية: Publisher: Chinese Medical Association Country of Publication: China NLM ID: 16210370R Publication Model: Print Cited Medium: Print ISSN: 0529-567X (Print) Linking ISSN: 0529567X NLM ISO Abbreviation: Zhonghua Fu Chan Ke Za Zhi Subsets: MEDLINE
أسماء مطبوعة: Publication: Peking : Chinese Medical Association
Original Publication: Beiping [1953?]-
مواضيع طبية MeSH: Anemia/*diagnosis , Cardiotocography/*methods , Fetal Hypoxia/*diagnosis , Heart Rate, Fetal/*physiology, Adult ; Anemia/physiopathology ; Blood Gas Analysis ; Female ; Fetal Diseases/diagnosis ; Fetal Diseases/physiopathology ; Fetal Hypoxia/physiopathology ; Hemoglobins/analysis ; Humans ; Hydrogen-Ion Concentration ; Infant, Newborn ; Pregnancy ; Pregnancy Outcome ; Pregnancy Trimester, Third ; Retrospective Studies ; Umbilical Arteries/chemistry
مستخلص: Objective: To investigate clinical significance of intermittent sinusoidal fetal heart rate at third trimester.
Methods: From Jan 2002 to Dec 2010, 48 pregnant women at 33 to 41 gestational weeks undergoing electronic fetal heart rate (FHR) monitoring presented with intermittent sinusoidal FHR in Department of Obstetrics and Gynecology, Second School of Clinical Medicine, Jinan University were enrolled in this retrospective study. Twenty-one cases were categorized into continuous group (i.e. with sinusoidal feature and a constant duration ≥ 10 minutes), while the other 27 cases were categorized into intermittent group (i.e. with a duration < 10 minutes). In the mean time, 76 normal cases were chosen randomly matched as control group. Blood gas and hemoglobin were measured in umbilical artery after fetal head delivery. General neurological system examination were performed in those fetus in hospitalization. The outcome of those fetuses was compared.
Results: (1) Neonatal complications: the rate of asphyxia, meconium-stained amniotic fluid and fetal anemia were 63% (17/27), 33% (9/27) and 63% (17/27) in group of intermittent sinusoidal FHR, which were significantly higher than 1% (1/76), 4% (3/76), 3% (2/76) in control group (P < 0.05). When compared with 67% (14/21), 52% (11/21), 76% (16/21) in group of continuous sinusoidal, the statistical difference were not observed (P > 0.05). (2) Blood gas in neonate: the rates of pH less than 7 were 18% (5/27) in intermittent group, 52% (11/21) in continuous group and 0 in control group, which all reached statistical difference among those three groups (P < 0.05). (3) Brain damage and death: the rates of brain damage and death were 48% (13/27) and 11% (3/27) in intermittent group, 81% (17/21) and 43% (9/21) in continuous group, and 0 in control group, which all showed significant difference between them (P < 0.05).
Conclusion: Intermittent and continuous sinusoidal FHR are typical graphics of severe fetal anemia at third trimester. Intermittent sinusoidal FHR is indicative of serious fetal hypoxia.
المشرفين على المادة: 0 (Hemoglobins)
تواريخ الأحداث: Date Created: 20110708 Date Completed: 20120524 Latest Revision: 20110707
رمز التحديث: 20221213
PMID: 21733369
قاعدة البيانات: MEDLINE