[Efficacy of fibrin tissue adhesive in the attachment of autogenous conjuntival graft on primary pterygium surgery].

التفاصيل البيبلوغرافية
العنوان:	[Efficacy of fibrin tissue adhesive in the attachment of autogenous conjuntival graft on primary pterygium surgery].
عنوان ترانسليتريتد:	Eficácia do adesivo tecidual de fibrina na fixação de enxerto conjuntival autógeno em cirurgias de pterígio primário.
المؤلفون:	Rubin MR; Departamento de Oftalmologia, Irmandade da Santa Casa de Misericórdia de São Paulo, SP, Brasil. rubinmichel@hotmail.com, Dantas PE, Nishiwaki-Dantas MC, Felberg S
المصدر:	Arquivos brasileiros de oftalmologia [Arq Bras Oftalmol] 2011 Mar-Apr; Vol. 74 (2), pp. 123-6.
نوع المنشور:	Comparative Study; Journal Article; Randomized Controlled Trial; Validation Study
اللغة:	Portuguese
بيانات الدورية:	Publisher: Conselho Brasileiro de Oftalmologia Country of Publication: Brazil NLM ID: 0400645 Publication Model: Print Cited Medium: Internet ISSN: 1678-2925 (Electronic) Linking ISSN: 00042749 NLM ISO Abbreviation: Arq Bras Oftalmol Subsets: MEDLINE
أسماء مطبوعة:	Publication: São Paulo : Conselho Brasileiro de Oftalmologia Original Publication: São Paulo.
مواضيع طبية MeSH:	Suture Techniques, Conjunctiva/transplantation , Fibrin Tissue Adhesive/therapeutic use , Pterygium/surgery, Adolescent ; Adult ; Aged ; Humans ; Hyperemia ; Middle Aged ; Postoperative Complications ; Postoperative Period ; Prospective Studies ; Statistics, Nonparametric ; Time Factors ; Transplantation, Autologous/methods ; Treatment Outcome ; Young Adult
مستخلص:	Purpose: To compare the efficacy of conjunctival autograft surgery with the attachment to the scleral bed using fibrin tissue adhesive or mononylon 10-0 suture after resection of primary pterygium. Methods: A comparative, prospective and randomized clinical trial was performed in 47 eyes of 47 patients with primary medial located pterygium. Group 1 (adhesive) was composed by 21 patients that underwent conjunctival autograft closure with fibrin tissue adhesive (Quixil™) and Group 2 (suture) was composed by 26 patients that underwent pterygium surgery with mononylon 10-0 (Ethicon(®)) suture (suture group) after pterygium excision. All surgeries were performed by the same surgeon. Patients were assessed on the preoperative period and on the 1(st), 14(th) and 21(st) postoperative days. They were followed-up with a questionnaire of ocular discomfort and by the surgical time spent, ocular hyperemia, complications and recurrence signals, being the recurrence also evaluated at the 6th postoperative month. Data were submitted to statistical analysis. A value of p<0.005 was considered statistically significant. Results: The average surgical time was 19.05 ± 6.12 minutes in group 1 (glue) and 48.15 ± 7.13 minutes in the group 2 (suture) (p<0.001). The ocular discomfort scale analysis showed a lower score in the 1(st) (p<0.005), 7(th) (p<0.001) and 21(th) (p<0.001) postoperative days in group 1. Ocular hyperemia was less intense in all periods of this study in group 1 (p<0.001). Complications were one in each group and both were managed with clinical treatment until the 21(th) postoperative day. There was one recurrence in group 1 and two in group 2 until the 6(th) postoperative month. Conclusion: In the surgical management of primary pterygium, fibrin tissue adhesive attached the conjunctival autograft, decreased the surgical time and diminished the conjunctival hyperemia and ocular discomfort with similar recurrences on the postoperative period, compared to fixation with mononylon 10.0 suture, proving to be an excellent option for conjunctival autograft attachment in primary pterygium surgery.
المشرفين على المادة:	0 (Fibrin Tissue Adhesive)
تواريخ الأحداث:	Date Created: 20110723 Date Completed: 20120119 Latest Revision: 20191210
رمز التحديث:	20231215
DOI:	10.1590/s0004-27492011000200011
PMID:	21779669
قاعدة البيانات:	MEDLINE

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تدمد:	1678-2925
DOI:	10.1590/s0004-27492011000200011