دورية أكاديمية
Somatotroph pituitary tumors in budgerigars (Melopsittacus undulatus).
| العنوان: | Somatotroph pituitary tumors in budgerigars (Melopsittacus undulatus). |
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| المؤلفون: | Langohr IM; Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA. langohri@dcpah.msu.edu, Garner MM, Kiupel M |
| المصدر: | Veterinary pathology [Vet Pathol] 2012 May; Vol. 49 (3), pp. 503-7. Date of Electronic Publication: 2011 Sep 07. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Sage Country of Publication: United States NLM ID: 0312020 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1544-2217 (Electronic) Linking ISSN: 03009858 NLM ISO Abbreviation: Vet Pathol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Jan. 2010- : Thousand Oaks, CA : Sage Original Publication: 1971- : Basel : New York : Karger. |
| مواضيع طبية MeSH: | Animals, Zoo* , Melopsittacus*, Adenoma, Chromophobe/*veterinary , Bird Diseases/*pathology , Pituitary Neoplasms/*veterinary, Adenoma, Chromophobe/pathology ; Animals ; Fatal Outcome ; Immunohistochemistry/veterinary ; Pituitary Hormones/metabolism ; Pituitary Neoplasms/pathology |
| مستخلص: | A series of 11 pituitary tumors in budgerigars were classified on the basis of their clinical, gross, microscopic, and immunohistochemical characteristics. Affected birds were young to middle-aged. Clinically, neurologic signs--including difficulties flying, ataxia, and blindness--were most commonly reported. Additional clinical signs included weight loss, abnormal feathers or molting, increased respiratory efforts, and exophthalmos. Nine birds were diagnosed with chromophobic pituitary adenomas, and 2 birds had chromophobic pituitary carcinomas. Only 1 tumor was delimited to the pituitary gland; the other 10 variably invaded the brain, skull, and retrobulbar space. Distant metastases were identified in 2 birds. All tumors were immunohistochemically strongly positive for growth hormone, consistent with the diagnosis of somatotroph tumors. The common occurrence and early onset may suggest a genetic predisposition of budgerigars to develop somatotroph pituitary tumors with a high incidence of local invasion and with metastatic potential. |
| المشرفين على المادة: | 0 (Pituitary Hormones) |
| تواريخ الأحداث: | Date Created: 20110909 Date Completed: 20120822 Latest Revision: 20120427 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1177/0300985811419530 |
| PMID: | 21900544 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1544-2217 |
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| DOI: | 10.1177/0300985811419530 |