دورية أكاديمية
أعرض في EDS

Severity assessment of pulmonary embolism using dual energy CT - correlation of a pulmonary perfusion defect score with clinical and morphological parameters of blood oxygenation and right ventricular failure.

التفاصيل البيبلوغرافية
العنوان: Severity assessment of pulmonary embolism using dual energy CT - correlation of a pulmonary perfusion defect score with clinical and morphological parameters of blood oxygenation and right ventricular failure.
المؤلفون: Thieme SF; Department of Clinical Radiology, Ludwig-Maximilians-Universität, Klinikum Großhadern, Marchioninistr.15, 81377 München, Germany. sven.thieme@med.uni-muenchen.de, Ashoori N, Bamberg F, Sommer WH, Johnson TR, Leuchte H, Becker A, Maxien D, Helck AD, Behr J, Reiser MF, Nikolaou K
المصدر: European radiology [Eur Radiol] 2012 Feb; Vol. 22 (2), pp. 269-78. Date of Electronic Publication: 2011 Sep 14.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer International Country of Publication: Germany NLM ID: 9114774 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1084 (Electronic) Linking ISSN: 09387994 NLM ISO Abbreviation: Eur Radiol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Berlin : Springer International, c1991-
مواضيع طبية MeSH: Blood/*metabolism , Cardiology/*methods , Lung/*metabolism , Oxygen/*metabolism , Pulmonary Embolism/*diagnosis , Pulmonary Embolism/*diagnostic imaging , Tomography, X-Ray Computed/*methods , Ventricular Dysfunction, Right/*metabolism, Aged ; Contrast Media/pharmacology ; Female ; Humans ; Iohexol/analogs & derivatives ; Iohexol/pharmacology ; Lung/diagnostic imaging ; Male ; Middle Aged ; Perfusion
مستخلص: Objective: To correlate a Dual Energy (DE)-based visual perfusion defect scoring system with established CT-based and clinical parameters of pulmonary embolism (PE) severity.
Methods: In 63 PE patients, DE perfusion maps were visually scored for perfusion defects (P-score). Vascular obstruction was quantified using the Mastora score. Both scores were correlated with short-axis diameters of the right and left ventricle, their ratio (RV/LV ratio), width of the pulmonary trunk, a number of clinical parameters and each other. Univariate and multivariate analyses were performed. Times to generate both scores were recorded.
Results: After univariate and multivariate analysis, a significant (p < 0.05) correlation with the P-score was shown for the Mastora score (r = 0.65), RV/LV ratio (r = 0.47), width of the pulmonary trunk (r = 0.26), troponin I (r = 0.43) and PaO(2) (r = -0.50). For the left ventricular diameter, only univariate analysis showed a significant correlation. Mastora score correlated significantly with RV/LV ratio (r = 0.36), width of the pulmonary trunk (r = 0.27), PaO(2) (r = -0.41) and troponin I (r = 0.37). Mean time for generating the P-score was significantly shorter than for the Mastora score.
Conclusions: A DE-based P-score correlates with a number of parameters of PE severity. It might be easier and faster to perform than some traditional CT scoring methods for vascular obstruction.
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المشرفين على المادة: 0 (Contrast Media)
4419T9MX03 (Iohexol)
712BAC33MZ (iopromide)
S88TT14065 (Oxygen)
تواريخ الأحداث: Date Created: 20110914 Date Completed: 20120619 Latest Revision: 20211020
رمز التحديث: 20240628
DOI: 10.1007/s00330-011-2267-3
PMID: 21913059
قاعدة البيانات: MEDLINE
الوصف
تدمد:1432-1084
DOI:10.1007/s00330-011-2267-3