دورية أكاديمية

The effects of carbohydrate ingestion during endurance running on post-exercise inflammation and hepcidin levels.

التفاصيل البيبلوغرافية
العنوان: The effects of carbohydrate ingestion during endurance running on post-exercise inflammation and hepcidin levels.
المؤلفون: Sim M; School of Sport Science, Exercise and Health, The University of Western Australia, 35 Stirling Hwy, Crawley, WA 6009, Australia. simm08@student.uwa.edu.au, Dawson B, Landers G, Wiegerinck ET, Swinkels DW, Townsend MA, Trinder D, Peeling P
المصدر: European journal of applied physiology [Eur J Appl Physiol] 2012 May; Vol. 112 (5), pp. 1889-98. Date of Electronic Publication: 2011 Sep 16.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 100954790 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-6327 (Electronic) Linking ISSN: 14396319 NLM ISO Abbreviation: Eur J Appl Physiol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Berlin ; New York : Springer-Verlag, c2000-
مواضيع طبية MeSH: Antimicrobial Cationic Peptides/*blood , Dietary Carbohydrates/*pharmacology , Exercise/*physiology , Inflammation/*blood , Iron/*blood , Running/*physiology, Cytokines/blood ; Dietary Carbohydrates/administration & dosage ; Exercise Test ; Hemolysis ; Hepcidins ; Humans ; Male ; Physical Endurance/physiology ; Young Adult
مستخلص: The effect of carbohydrate (CHO) consumption during prolonged endurance running on post-exercise inflammation and hepcidin levels was investigated. Eleven well-trained male endurance athletes completed a graded exercise test, followed by two experimental running trials in a randomized order. The two experimental trials consisted of a 90 min run at 75% of the peak oxygen uptake velocity (vVO(2peak)), while consuming a solution with either 6% CHO or a placebo (PLA) equivalent at 3 ml kg(-1) every 20 min. Serum interleukin-6 (IL-6), free hemoglobin (Hb), haptoglobin (Hp), hepcidin and iron parameters were assessed throughout the post-run recovery period. Serum iron and IL-6 were significantly elevated immediately post-run in both CHO and PLA (p ≤ 0.05), with no differences between trials. Serum-free Hb increased and Hp decreased significantly immediately post-run in both conditions (p ≤ 0.05). Serum soluble transferrin receptor levels were significantly below the baseline at 3 and 24 h post-run in both conditions (p ≤ 0.05). Serum hepcidin concentration recorded 3 h post-run in both conditions was significantly elevated (p ≤ 0.05), and had returned to the baseline by 24 h post-run (p ≤ 0.05). The use of a 6% CHO solution at 3 ml kg(-1) 20 min(-1) during endurance running did not attenuate the inflammatory response and subsequent increase in serum hepcidin levels during the post-run recovery period.
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المشرفين على المادة: 0 (Antimicrobial Cationic Peptides)
0 (Cytokines)
0 (Dietary Carbohydrates)
0 (HAMP protein, human)
0 (Hepcidins)
E1UOL152H7 (Iron)
تواريخ الأحداث: Date Created: 20110917 Date Completed: 20130501 Latest Revision: 20211020
رمز التحديث: 20231215
DOI: 10.1007/s00421-011-2156-0
PMID: 21922263
قاعدة البيانات: MEDLINE
الوصف
تدمد:1439-6327
DOI:10.1007/s00421-011-2156-0