دورية أكاديمية
The effects of carbohydrate ingestion during endurance running on post-exercise inflammation and hepcidin levels.
العنوان: | The effects of carbohydrate ingestion during endurance running on post-exercise inflammation and hepcidin levels. |
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المؤلفون: | Sim M; School of Sport Science, Exercise and Health, The University of Western Australia, 35 Stirling Hwy, Crawley, WA 6009, Australia. simm08@student.uwa.edu.au, Dawson B, Landers G, Wiegerinck ET, Swinkels DW, Townsend MA, Trinder D, Peeling P |
المصدر: | European journal of applied physiology [Eur J Appl Physiol] 2012 May; Vol. 112 (5), pp. 1889-98. Date of Electronic Publication: 2011 Sep 16. |
نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
اللغة: | English |
بيانات الدورية: | Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 100954790 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-6327 (Electronic) Linking ISSN: 14396319 NLM ISO Abbreviation: Eur J Appl Physiol Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Berlin ; New York : Springer-Verlag, c2000- |
مواضيع طبية MeSH: | Antimicrobial Cationic Peptides/*blood , Dietary Carbohydrates/*pharmacology , Exercise/*physiology , Inflammation/*blood , Iron/*blood , Running/*physiology, Cytokines/blood ; Dietary Carbohydrates/administration & dosage ; Exercise Test ; Hemolysis ; Hepcidins ; Humans ; Male ; Physical Endurance/physiology ; Young Adult |
مستخلص: | The effect of carbohydrate (CHO) consumption during prolonged endurance running on post-exercise inflammation and hepcidin levels was investigated. Eleven well-trained male endurance athletes completed a graded exercise test, followed by two experimental running trials in a randomized order. The two experimental trials consisted of a 90 min run at 75% of the peak oxygen uptake velocity (vVO(2peak)), while consuming a solution with either 6% CHO or a placebo (PLA) equivalent at 3 ml kg(-1) every 20 min. Serum interleukin-6 (IL-6), free hemoglobin (Hb), haptoglobin (Hp), hepcidin and iron parameters were assessed throughout the post-run recovery period. Serum iron and IL-6 were significantly elevated immediately post-run in both CHO and PLA (p ≤ 0.05), with no differences between trials. Serum-free Hb increased and Hp decreased significantly immediately post-run in both conditions (p ≤ 0.05). Serum soluble transferrin receptor levels were significantly below the baseline at 3 and 24 h post-run in both conditions (p ≤ 0.05). Serum hepcidin concentration recorded 3 h post-run in both conditions was significantly elevated (p ≤ 0.05), and had returned to the baseline by 24 h post-run (p ≤ 0.05). The use of a 6% CHO solution at 3 ml kg(-1) 20 min(-1) during endurance running did not attenuate the inflammatory response and subsequent increase in serum hepcidin levels during the post-run recovery period. |
References: | Exerc Sport Sci Rev. 1993;21:297-330. (PMID: 8504845) Int J Sport Nutr Exerc Metab. 2009 Dec;19(6):583-97. (PMID: 20175428) J Appl Physiol (1985). 2003 Jan;94(1):38-42. (PMID: 12391035) Am J Clin Nutr. 2000 Aug;72(2 Suppl):594S-7S. (PMID: 10919965) Med Sci Sports Exerc. 1992 Sep;24(9 Suppl):S324-30. (PMID: 1406205) J Appl Physiol Respir Environ Exerc Physiol. 1983 Jul;55(1 Pt 1):230-5. (PMID: 6350247) J Appl Physiol (1985). 2004 Apr;96(4):1285-91. (PMID: 14657044) Cytokine. 2011 Feb;53(2):196-200. (PMID: 21095135) Eur J Appl Physiol. 2003 Jun;89(5):500-2. (PMID: 12712355) J Lab Clin Med. 1989 Oct;114(4):368-77. (PMID: 2677198) Med Sci Sports Exerc. 1998 May;30(5):671-8. (PMID: 9588607) J Clin Invest. 2004 May;113(9):1271-6. (PMID: 15124018) Curr Med Chem. 2005;12(23):2741-51. (PMID: 16305469) J Hepatol. 2003 Nov;39(5):710-5. (PMID: 14568251) Eur J Appl Physiol. 2005 Dec;95(5-6):569-71. (PMID: 16249921) J Appl Physiol (1985). 1997 May;82(5):1662-7. (PMID: 9134917) Br J Haematol. 2001 Oct;115(1):84-9. (PMID: 11722416) Blood. 1990 Apr 15;75(8):1602-5. (PMID: 2328312) Clin J Sport Med. 2003 Sep;13(5):309-18. (PMID: 14501315) J Sports Sci. 1996 Aug;14(4):321-7. (PMID: 8887211) Nutrition. 2004 Jul-Aug;20(7-8):632-44. (PMID: 15212745) Brain Res Bull. 1995;36(5):505-13. (PMID: 7712215) Curr Opin Hematol. 2001 May;8(3):137-41. (PMID: 11303145) J Physiol. 2003 Jan 1;546(Pt 1):299-305. (PMID: 12509497) Blood. 1990 Jan 1;75(1):102-7. (PMID: 2294984) Clin Chem Lab Med. 1999 Jan;37(1):1-10. (PMID: 10094372) J Biophys Biochem Cytol. 1957 May 25;3(3):503-4. (PMID: 13438933) Eur J Appl Physiol. 2008 Jul;103(4):381-91. (PMID: 18365240) Med Sci Sports Exerc. 2000 Oct;32(10):1783-9. (PMID: 11039653) Br J Sports Med. 2002 Jun;36(3):195-9. (PMID: 12055114) J Appl Physiol (1985). 1993 Dec;75(6):2774-80. (PMID: 8125902) Clin J Sport Med. 2001 Jan;11(1):38-43. (PMID: 11176144) Eur J Appl Physiol. 2009 May;106(1):51-9. (PMID: 19184087) Physiol Res. 1999;48(6):473-82. (PMID: 10783913) FASEB J. 2001 Dec;15(14):2748-50. (PMID: 11687509) Blood. 1992 Jul 15;80(2):420-8. (PMID: 1627800) Science. 2004 Dec 17;306(5704):2090-3. (PMID: 15514116) Nephrol Dial Transplant. 2002;17 Suppl 11:39-43. (PMID: 12386257) J Physiol. 2001 Dec 1;537(Pt 2):633-9. (PMID: 11731593) Med Sci Sports Exerc. 2005 Mar;37(3):426-32. (PMID: 15741841) J Appl Physiol (1985). 1993 Nov;75(5):2168-72. (PMID: 8307875) J Immunol. 2004 Jul 15;173(2):715-20. (PMID: 15240655) J Appl Physiol (1985). 2004 Apr;96(4):1277-84. (PMID: 14657042) Med Sci Sports Exerc. 2009 May;41(5):1138-45. (PMID: 19346972) Clin Chim Acta. 2004 Jul;345(1-2):35-42. (PMID: 15193975) |
المشرفين على المادة: | 0 (Antimicrobial Cationic Peptides) 0 (Cytokines) 0 (Dietary Carbohydrates) 0 (HAMP protein, human) 0 (Hepcidins) E1UOL152H7 (Iron) |
تواريخ الأحداث: | Date Created: 20110917 Date Completed: 20130501 Latest Revision: 20211020 |
رمز التحديث: | 20231215 |
DOI: | 10.1007/s00421-011-2156-0 |
PMID: | 21922263 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1439-6327 |
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DOI: | 10.1007/s00421-011-2156-0 |