دورية أكاديمية

Rejuvenation of periorbital area: treatment with an injectable nonanimal non-crosslinked glycerol added hyaluronic acid preparation.

التفاصيل البيبلوغرافية
العنوان: Rejuvenation of periorbital area: treatment with an injectable nonanimal non-crosslinked glycerol added hyaluronic acid preparation.
المؤلفون: Succi IB; Dermatology Department, Hospital Universitário Pedro Ernesto, Rio de Janeiro, Brazil., da Silva RT, Orofino-Costa R
المصدر: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] [Dermatol Surg] 2012 Feb; Vol. 38 (2), pp. 192-8. Date of Electronic Publication: 2011 Oct 14.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Wolters Kluwer Health Country of Publication: United States NLM ID: 9504371 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4725 (Electronic) Linking ISSN: 10760512 NLM ISO Abbreviation: Dermatol Surg Subsets: MEDLINE
أسماء مطبوعة: Publication: 2021- : [Philadelphia] : Wolters Kluwer Health
Original Publication: New York, NY : Elsevier Science, c1995-
مواضيع طبية MeSH: Face* , Rejuvenation* , Skin Aging*, Glycerol/*administration & dosage , Hyaluronic Acid/*administration & dosage, Adult ; Female ; Glycerol/adverse effects ; Humans ; Hyaluronic Acid/adverse effects ; Injections, Intradermal ; Middle Aged
مستخلص: Background: Therapeutic approaches to aging of the periorbital region are unique because of the delicacy of the anatomical structures and the possibility of adverse events. The synthesis of hyaluronic acid (HA) and other components responsible for skin hydration and elasticity diminish with age.
Objective: To evaluate the efficacy and safety of an injectable product containing non-crosslinked HA of nonanimal origin in association with glycerol to treat aging of the periorbital region.
Materials and Methods: A pilot study in which 20 women were administered three monthly superficial intradermal injections of non-crosslinked HA of nonanimal origin containing glycerol in the periorbital area. The clinical results consisted of the evaluation of three researchers and an independent evaluator and the degree of posttreatment patient satisfaction.
Results: An improvement of between 25% and 50% in skin brightness, texture, and turgor was observed in the periorbital area. Papules were present after each application, and hematoma was the longest lasting effect. All adverse events were reversible and well tolerated.
Conclusion: Injections of HA of nonanimal origin, in association with glycerol, using a micropuncture technique are well tolerated and can improve skin brightness and turgor and reduce roughness in the periorbital region.
(© 2011 by the American Society for Dermatologic Surgery, Inc. Published by Wiley Periodicals, Inc.)
المشرفين على المادة: 9004-61-9 (Hyaluronic Acid)
PDC6A3C0OX (Glycerol)
تواريخ الأحداث: Date Created: 20111119 Date Completed: 20120319 Latest Revision: 20220410
رمز التحديث: 20240829
DOI: 10.1111/j.1524-4725.2011.02182.x
PMID: 22092545
قاعدة البيانات: MEDLINE
الوصف
تدمد:1524-4725
DOI:10.1111/j.1524-4725.2011.02182.x