دورية أكاديمية
أعرض في EDS

Angiogenesis in head and neck cancer: a review of the literature.

التفاصيل البيبلوغرافية
العنوان: Angiogenesis in head and neck cancer: a review of the literature.
المؤلفون: Carla C; Division of Medical Oncology, A.O. San Paolo Via di Rudinì 8, 20122 Milan, Italy., Daris F, Cecilia B, Francesca B, Francesca C, Paolo F
المصدر: Journal of oncology [J Oncol] 2012; Vol. 2012, pp. 358472. Date of Electronic Publication: 2011 Nov 10.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Hindawi Publishing Corporation Country of Publication: Egypt NLM ID: 101496537 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1687-8469 (Electronic) Linking ISSN: 16878450 NLM ISO Abbreviation: J Oncol Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Cairo : Hindawi Publishing Corporation
مستخلص: Angiogenesis is a necessary process for tumor growth, progression and diffusion. In the last years many efforts have been made to understand the mechanisms necessary to the formation of new vessels in tumor tissue and how to integrate these findings in the treatment of different type of cancer. Thanks to these studies there are today many anti-angiogenic drugs with established activity in cancer and approved in clinical practice. Head and neck cancer is a common tumor worldwide that often has advanced stage at diagnosis and poor prognosis. Angiogenesis has a well recognized role in head and neck cancer progression and resistance to drugs and radiotherapy and many clinical trials has been conducted with antiangiogenic agents in this disease, even if they often showed limited efficacy. In this review we summarize the main trials published about angiogenesis in head and neck cancer with particular attention to factors involved in this process and the available data on the efficacy of treatment with anti-angiogenic agents in this disease.
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تواريخ الأحداث: Date Created: 20111202 Date Completed: 20120823 Latest Revision: 20211021
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC3216268
DOI: 10.1155/2012/358472
PMID: 22131994
قاعدة البيانات: MEDLINE
الوصف
تدمد:1687-8469
DOI:10.1155/2012/358472