دورية أكاديمية
Apelin in acute myocardial infarction and heart failure induced by ischemia.
| العنوان: | Apelin in acute myocardial infarction and heart failure induced by ischemia. |
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| المؤلفون: | Tycinska AM; Department of Cardiology, Medical University of Bialystok, Bialystok, Poland. agnieszka.tycinska@gmail.com, Lisowska A, Musial WJ, Sobkowicz B |
| المصدر: | Clinica chimica acta; international journal of clinical chemistry [Clin Chim Acta] 2012 Feb 18; Vol. 413 (3-4), pp. 406-10. Date of Electronic Publication: 2011 Nov 25. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 1302422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3492 (Electronic) Linking ISSN: 00098981 NLM ISO Abbreviation: Clin Chim Acta Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Amsterdam, Elsevier. |
| مواضيع طبية MeSH: | Heart Failure/*etiology , Heart Failure/*metabolism , Intercellular Signaling Peptides and Proteins/*metabolism , Myocardial Infarction/*etiology , Myocardial Infarction/*metabolism , Myocardial Ischemia/*complications, Acute Disease ; Animals ; Gene Expression Regulation ; Heart Failure/pathology ; Heart Failure/physiopathology ; Humans ; Myocardial Infarction/pathology ; Myocardial Infarction/physiopathology |
| مستخلص: | Apelin is a recently isolated novel endogenous ligand for the angiotensin-like 1 receptor (APJ). Initial experiments in animal models indicate that the cardiovascular system is the main target of the apelin-APJ system. Apelin plays an opposite role to the renin-angiotensin-aldosterone system as a compensatory mechanism. It is reduced in patients with heart failure, also of ischemic origin. However, only animal studies concern the role of the apelin-APJ system in myocardial ischemia. Less is known about the function of this adipokine in an acute phase of myocardial infarction in human. The apelin-APJ system could perhaps be involved in myocardial protection during acute myocardial ischemia. In the current review we have summarized recent data concerning the role of apelin in acute myocardial infarction and heart failure induced by ischemia. (Copyright © 2011 Elsevier B.V. All rights reserved.) |
| المشرفين على المادة: | 0 (Intercellular Signaling Peptides and Proteins) |
| تواريخ الأحداث: | Date Created: 20111208 Date Completed: 20120416 Latest Revision: 20220331 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1016/j.cca.2011.11.021 |
| PMID: | 22146598 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1873-3492 |
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| DOI: | 10.1016/j.cca.2011.11.021 |