دورية أكاديمية
A multicentre study on the reliability of qualitative and quantitative nail-fold videocapillaroscopy assessment.
| العنوان: | A multicentre study on the reliability of qualitative and quantitative nail-fold videocapillaroscopy assessment. |
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| المؤلفون: | Hofstee HM; Department of Internal Medicine, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands. hma.hofstee@vumc.nl, Serné EH, Roberts C, Hesselstrand R, Scheja A, Moore TL, Wildt M, Manning JB, Vonk Noordegraaf A, Voskuyl AE, Herrick AL |
| المصدر: | Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2012 Apr; Vol. 51 (4), pp. 749-55. Date of Electronic Publication: 2011 Dec 20. |
| نوع المنشور: | Journal Article; Multicenter Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: England NLM ID: 100883501 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1462-0332 (Electronic) Linking ISSN: 14620324 NLM ISO Abbreviation: Rheumatology (Oxford) Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Oxford, UK : Avenel, N.J. : Oxford University Press ; Distributed by Mercury International, c1999- |
| مواضيع طبية MeSH: | Microscopic Angioscopy/*methods , Nails/*blood supply , Raynaud Disease/*pathology , Scleroderma, Systemic/*pathology, Capillaries/pathology ; Humans ; Observer Variation ; Reproducibility of Results ; Single-Blind Method ; Video Recording |
| مستخلص: | Objective: To investigate the inter- and intra-observer reliability of both qualitative and quantitative parameters used in the assessment of nail-fold capillaroscopy images. Methods: Fifty mosaic nail-fold images of healthy controls (n = 10), patients with primary RP (n = 10) and SSc (n = 30) were assessed in random order by two blinded observers on two occasions at centres in Sweden, UK and The Netherlands. Each image was therefore scored by six observers twice. Results: Inter- and intra-observer reliability of quantitative parameters showed substantial to almost perfect agreement [inter- and intra-observer weighted κ's for the number of widened capillaries was 0.75 and 0.87 and giant capillaries was 0.84 and 0.92, intra-class correlation coefficients (ICCs) for capillary density was 0.87 and 0.92 and total loop width was 0.94 and 0.98, respectively]. Qualitative parameters including architecture, avascularity, haemorrhage, crossed, ramified and bushy capillaries showed moderate to substantial inter-observer reproducibility (weighted κ ranging from 0.47 to 0.73), and substantial intra-observer repeatability (weighted κ ranging from 0.71 to 0.80), whereas the scoring of tortuous and bizarre capillaries showed poor inter-observer and substantial intra-observer agreement (inter-observer weighted κ's was 0.39 and 0.21 and intra-observer weighted κ's was 0.68 and 0.76, respectively). Conclusion: All quantitative and certain qualitative parameters are highly reliable in terms of inter- and intra-observer agreement. A combination of parameters with the highest reliability should be incorporated into future capillaroscopic scoring systems in studies of prediction and monitoring of SSc spectrum disorders. |
| التعليقات: | Comment in: Rheumatology (Oxford). 2012 Oct;51(10):1921-2; author reply 1922. (PMID: 22772318) |
| تواريخ الأحداث: | Date Created: 20111223 Date Completed: 20120508 Latest Revision: 20121120 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1093/rheumatology/ker403 |
| PMID: | 22190689 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1462-0332 |
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| DOI: | 10.1093/rheumatology/ker403 |